Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Resistin"”.
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Effects of Growth Hormone on Circulating Resistin Levels in Mice
… in proinflammatory hormones. One such adipokine, resistin, is found to have a positive correlation with inflammation and with insulin resistance. The aim of this study was to investigate circulating resistin levels in three mouse lines with altered growth hormone (GH) action. Bovine growth hormone …
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Implication of homocysteine, resistin and vitamin D in development of type 2 diabetes
… of insulin resistance, among them vitamin D, resistin and homocysteine which can interrupt the insulin signalling pathway leading to insulin resistance. Elevated levels of homocysteine have been observed in patients with T2DM and metabolic syndrome, while resistin (a hormone) was suggested to …
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The effects of the adipocyte-secreted proteins resistin and visfatin on the pancreatic beta-cell
… link between obesity and type 2 diabetes (T2D). Resistin and visfatin are two adipokines which have been previously suggested as having roles in the pancreatic islet. The aim of this study was therefore to investigate the regulatory role of the adipokines resistin and visfatin in the pancreatic …
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The Effect of Weight Reduction on Chronic Inflammatory Molecules and Insulin Resistance in type 2 DM
… inflammatory molecules (etc: TNF-a, IL-6, IL-10, resistin, leptin, adiponectin) and the insulin signaling cascade including insulin receptor(IR-β), insulin receptor substrate(IRS)-1, Akt, and GSK-3, PAC-zeta, lambda, theta, delta, alpha, beta phosphorylation before and after insulin stimulation in …
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Improving outcomes for obese children with Acute Lymphoblastic Leukaemia (ALL): a clinical collaboration to understand the influence of obesity on treatment success.
… endocan and adiponectin in weight gain. Also, resistin, serpin A12, IGFBP4, cathepsin-S and Angiopoetin-2 in MRD risk. We have shown that leptin, IL-8, serpin A12 and angiopoietin-2 have a protective effect when incubated with the Molt4 ALL cell line and that resistin does not offer this …
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Physiological and Performance Effects of 11 Weeks of Training in Division 1 Collegiate Throwers: An Exploratory Study.
… and adipokines (adiponectin, leptin, and resistin) were taken at weeks 1, 7, and 11. The throwers demonstrated several statistically significant alterations over time for performance variables. The throwers realized increases across time in maximum strength and peak power output. Hormone …
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Mapping Major Genetic Factors of Obesity
… cell-signaling molecules (adiponectin, leptin, resistin, tumor necrosis factor alpha, plasminogen activator inhibitor one, interleukin six, insulin, and oxytocin) involved in pathways that affect metabolism. Behaviors like hyperphagia and exercise are important aspects of both the development …
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The role of sex steroids in the regulation of the Obese gene and leptin secretion
… by estrogen that parallels the accumulation of Resistin mRNA, a known estrogen responsive gene. In contrast, dihydrotestosterone strongly reduces the Ob mRNA levels in 3T3-L1 adipocytes with effects detected at 0.1 nM, with maximal and significant effects at 10 nM following 12 hours of …
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Uždegimo žymenų reikšmė ankstyvam ūminio pankreatito eigos prognozavimui: perspektyvinio daugiacentrio kohortinio tyrimo rezultatai /
… are associated with more severe AP cases. Resistin, IL-6 and BISAP score were found to be the early markers of SAP. Only BISAP score was an early predictor of necrosis, needs for interventions and mortality.
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The value of inflammation markers in early acute pancreatitis course prediction: the results of prospective multicenter cohort study /
… are associated with more severe AP cases. Resistin, IL-6 and BISAP score were found to be the early markers of SAP. Only BISAP score was an early predictor of necrosis, needs for interventions and mortality.
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Exploring the influence of adipokines on neuronal function in Alzheimer’s disease
… available adipokines (chemerin, leptin and resistin) on neuronal-like cells and effect of chemerin on human skin fibroblast cells derived from AD and non-AD donors, MTT assay was performed in the presence and absence of H2O2 induced oxidative stress. Conclusively, the conditioned media and …
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Hypoxia induces selective neutrophil degranulation to promote endothelial damage in COPD
… release of selected cytotoxic granule (NE, resistin and neutrophil gelatinase-associated lipocalin) and cytoplasmic (cyclophilin A) proteins under hypoxia. Furthermore, a plasma signature of increased protease (NE and proteinase 3) activity was identified in COPD versus healthy control …
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Characterizing Host Protective Immune Responses to the Parasitic Worm Heligmosomoides polygyrus
… effective granulomas (chapter 1), the role of resistin like molecule (RELM) alpha, a protein shown to downregulate Th2 immunity (chapter 2), and eosinophils, an enigmatic cell type whose role in anti-worm immunity remains controversial (chapter 3). C57Bl/6 mice are susceptible to H. polygyrus …
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Polyunsaturated fatty acids and inflammatory biomarkers in the pathogenesis of type II diabetes
… an authentic standard. Cytokines (adiponectin, resistin, leptin, IL-1β, IL-6, IL-4, IL-8, IL-10, IL-12, TNF-α, IFN-γ, TGF-β and MCP-1) were measured by a multiplex assay that utilises Luminex software technology and vitamin D by chemiluminescence microparticle immunoassay methodology. The FA …
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Effect of obesity on hepatic drug metabolism
… Our studies indicate that individually, leptin, resistin, IL-6 and TNF-α can modulate expression of various DMEs in a concentration dependent and isoform specific manner. This study demonstrates that the obesity microenvironment is important in obesity mediated changes in drug metabolism. …
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Epicardial Adipose Tissue: Relationship with Cardiovascular Disease and the Effect of Therapeutic Interventions
… disease (CVD) such as TNFα, IL-6, IL-1β and resistin amongst others. Having considered evidence of the possible effect of EAT in the development of atherosclerosis, which is hugely limited to few studies, implied the importance of studying various drug therapies on EAT.<br/> <br/>Methodology …
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The Recruitment and Function of Tumor Microenvironment Components During Gastric Carcinogenesis
… mice had significantly higher levels of IL-6, resistin, and PAI-1, and were more glucose intolerant than uninfected obese mice. Myeloid proliferation was similar between the two groups (as measured by KI67 and BrdU), as well as myeloid chemotaxis from the blood into adipose tissue (as …
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Clinical and Molecular Analyses of Intestinal Goblet Cell Acidomucins and Cysteine Metabolism
… which include trefoil factor 3 (TFF3) and resistin like molecule β (RETNLB). Goblet cell mucins show great structural heterogeneity but can be broadly classified into neutral and acidic subtypes (chemotypes), which can be further classified into sulfomucins or sialomucins based on the …
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