Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"Resistance-Breaking"”.
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Small Core Heterocyclic Carbamates and Carboxamides: Resistance-breaking Acetylcholinesterase Inhibitors Targeting the Malaria Mosquito, Anopheles gambiae
… LC₅₀ Akron = 40 μg/mL). Hence, achieving the resistance- breaking goal. On the contrary, the commercial aryl methylcarbamates currently approved for indoor residual sprays (IRS) showed no potency towards the resistant strain An. gambiae (LC₅₀ G3 = 16-42 μg/mL, and LC₅₀ Akron >5,000 μg/mL). …
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Variability of the peanut mottle virus reaction in soybean (Glycine max)
… reaction of PMV in soybean, which could lead to resistance breaking strains, was investigated in this study. The specific research objectives were to provide evidence of PMV strains in soybean, and to characterize the PMV strains using aphid transmission efficiency and serological relationships. …
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Trifluoromethyl ketones: Potential insecticides towards Anopheles gambiae
… control measures are being threatened by growing resistance to pyrethroid insecticides. With the goal of developing new human-safe, resistance-breaking insecticides we have explored several classes of acetylcholinesterase inhibitors. In vitro assay studies have shown that trifluoromethyl ketones …
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Interactions of soybean Rsv genes and Soybean mosaic virus
… to the common strains of SMV. However, new resistance-breaking (RB) isolates of SMV have emerged in natural infections to break the resistance of Hutcheson containing the Rsv1y allele. These RB isolates are SMV-G5 and G6-like based on the differential reactions on soybean cultivars with the …
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Fluoromethyl ketone prodrugs: Potential new insecticides towards Anopheles gambiae
… control measures are being threatened by growing resistance to pyrethroid insecticides. With the goal of developing new human-safe, resistance-breaking insecticides we have explored several classes of acetylcholinesterase inhibitors. In vitro assay studies demonstrate that tri- and difluoromethyl …
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Engineering resistance to maize lethal necrosis
… susceptibility to emerging pathogens. Pathogen resistance may be developed through conventional breeding approaches, or a number of transgenic strategies. This thesis focuses on the characterisation of an emerging maize disease, Maize lethal necrosis (MLN), and engineering resistant maize lines …
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Intraspecific Variability within Globodera tabacum solanacearum and Selection for Virulence Against Flue-Cured Tobacco
… This result suggests that the emergence of resistance-breaking biotypes is more likely than previous research suggests. If a new pathotype is reported, a RAPD marker associated with virulence against a specific host resistance gene could prove to be a valuable tool in population diagnosis, …
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Evolutionary studies of wheat streak mosaic-associated viruses and characterization of the wheat virome
… viruses increases the emergence of potential resistance-breaking isolates. Currently, little is known about the genetic composition of populations of WSM-associated viruses in the field. This study first aims to analyze the genetic variation and characterize the evolutionary mechanism(s) …
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Modelling spatial strategies for the durable deployment of crop disease resistance
Maximising the durability of crop disease resistance genes in the face of pathogen evolution is a major challenge in modern agricultural epidemiology. Spatial diversification in the deployment of resistance genes, where susceptible and resistant fields are more closely intermixed, is predicted to …
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Soybean mosaic virus-soybean interactions: molecular, biochemical, physiological, and immunological analysis of resistance responses of soybean to soybean mosaic virus
Strain-specific resistance conditioned by a single dominant gene in soybean cv. York inoculated with SMV-G1, revealed no symptoms and no detectable viral replication (R). Unlike the hypersensitive response (HR), the R response did not result in localized virus and induction of a series of defense …
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Toxicological Analysis of Acaricides for Varroa Mite Management
… only have adverse health effects on bees, but resistance limits their use to reduce mites and diseases in bee colonies. Voltage-gated chloride channels are involved in the maintenance of nerve and muscle excitability in arthropod pests, which suggests that these channels might be exploited as …