Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 21 for “"Resistance alleles"”.
-
The occurence, distribution and frequency of membrane transporter resistance alleles in <i>Plasmodium falciparum</i> and their association with response and resistance to Arteminisin based combination therapy (ART) in Northern Nigeria
… genome has shown to have recently developed resistance to the most successful related group of drug treatment, known as Artemisinin combination therapies (ACTs), primarily in parts of South East Asia, but possibly also in other parts of the world e.g. East Africa.<br/>The purpose of this …
-
Interaction Between Soybean and Phytophthora Sojae
… tons in 1994 in the United States. Thirteen resistance alleles at seven loci have been identified in soybean that control race-specific resistance. There are currently 53 races of P. sojae. The resistant reaction appears to be effective in the early colonization stages of pathogenesis, with …
-
Allele dynamics in conjugative plasmids: Horizontal transfer promotes allele segregation in multicopy plasmids
The emergence of multidrug resistance and the spread of resistance genes among bacteria pose a major threat to human health. Plasmids, particularly through horizontal transfer, are considered key drivers of antimicrobial resistance spread because they can disseminate resistance alleles between …
-
A pan-genomics approach linking genotype and phenotype in the mega-pest, Helicoverpa armigera
… the genetic mechanisms that drive pesticide resistance is crucial for effective monitoring of resistance but remains challenging. Recent advances in sequencing technologies, specifically long-read sequencing, have dramatically improved the resolution of the genetic information able to be …
-
A pan-genomics approach linking genotype and phenotype in the mega-pest, Helicoverpa armigera
… the genetic mechanisms that drive pesticide resistance is crucial for effective monitoring of resistance but remains challenging. Recent advances in sequencing technologies, specifically long-read sequencing, have dramatically improved the resolution of the genetic information able to be …
-
Fitness Costs of Resistance to Bacillus thuringiensis in the Pink Bollworm Pectinophora gossypiella
Resistance to Bacillus thuringiensis (Bt) cotton, Gossypium hirsutum, is associated with fitness costs in pink bollworm, Pectinophora gossypiella. Previous work has demonstrated that costs of resistance are induced by environmental factors including insecticidal cotton phytochemicals such as …
-
Forward genetic analysis of cellulose biosynthesis inhibitor resistance and wall hydrolysis sensitivity.
… plants. Mutations resulting in a high degree of resistance to isoxaben (ixr) or flupoxam (fxr) were attributed to single amino acid substitutions in primary wall CESAs. Twelve novel resistance alleles were isolated and no cross-resistance was observed. Point mutations were mostly clustered around …
-
Empirical investigation of de novo mutations conferring herbicide resistance
… process, herbicides select for adaptive alleles that allow weed populations to survive. These resistance alleles may be available immediately from the standing genetic variation within the population, as well as, may immigrate via pollen or seeds from other populations. Moreover, because …
-
Does variability matter? Major histocompatibility complex (MHC) variation and its associations to parasitism in natural small mammal populations
… parasite burden in M. incanus due to a lack of resistance alleles. Parasitological results clearly reject the first scenario and point to the second scenario, as M. incanus is distinctly higher parasitised but parasite diversity is relatively equal compared to G. microtarsus. Hence, I suggest …
-
The evolutionary ecology of methylation-dependent bacterial defense systems
… Given the role of MGEs in spreading drug resistance alleles, the current focus on developing bacteriophages as alternative antimicrobials, and the ability for host defenses to interfere with both, it is essential to more fully understand these eco-evolutionary dynamics. As these dynamics …
-
Population Genetics and Phylogenetic Context of Weed Evolution in the Genus Amaranthus: Amaranthaceae)
… environment.</p><p>Waterhemp has rapidly evolved resistance to multiple classes of herbicides. The role of native Midwestern riverbank populations in this process is unknown. I screened agricultural and riverbank populations of <italic>A. tuberculatus</italic> in Ohio for a common agricultural …
-
Simultaneous Mapping and Pyramiding of Fusarium Head Blight Resistance Loci in Wheat Breeding Populations
… to enable markerassisted pyramiding for FHB resistance QTL. In the first study, we apply multipoint linkage analysis of general pedigrees to early generation wheat breeding populations for development of dense framework linkage maps. Using this approach, a linkage map consisting of 3,807 loci …
-
Genetic Analysis of the Resistance of Soybean Genotypes to Sclerotinia Sclerotiorum
… new genetic sources of sclerotinia stem rot resistance; (ii) determine the inheritance of field resistance to sclerotinia stem rot in a cross between the partially resistant cultivars Asgrow 'A2506' (A2506) and Novartis 'S19--90' (S19--90); (iii) determine the inheritance of field resistance …
-
Genetic Analysis and Marker -Assisted Selection of Scab Resistance QTL in Bread Wheat (Triticum Aestivum L.)
… three chromosomal regions associated with scab resistance were detected in a common cultivar, Ning7840. Interval analysis based on the integrated map of AFLP and SSR markers showed that the major 3BS QTL was located in a chromosome region about eight cM in length around Xgwm533 and Xbarc147. …
-
The Genetic Architecture Of Quantitative Disease Resistance In Maize
… the genetic basis for quantitative disease resistance (QDR) in plants. The focus of these studies was the economically important disease of maize (Zea mays L. ssp. mays), northern leaf blight (NLB, caused by Setosphaeria turcica L. anamorph Exserohilum turcicum). The maize nested association …
-
Molecular mapping of quantitative trait loci (QTL) for Fusarium head blight (FHB) resistance and agronomic traits in US hard winter wheat
… in grain yield and quality. Use of genetic resistance is an effective approach to FHB control, but highly FHB resistant germplasms usually have many undesirable agronomic traits. To dissect the relationship between FHB resistance and yield component traits, we developed two recombinant …
-
Restriction fragment length polymorphism mapping of quantitative and qualitative traits in soybean
… on a few major groups;Five Rps genes that confer resistance in soybean to phytophthora root rot caused by Phytophthora megasperma Drechs. f. sp. glycinea Kuan and Erwin were mapped with RFLP markers in the second study. The mapping was conducted by first screening, with RFLP markers, a series of …
-
Adaptation and hybridization in Helicoverpa crop pests
… hybridization, an allele conferring insecticide resistance was introduced into the native Brazilian H. zea population through adaptive introgression. I use this as a system with which to investigate the outcome of secondary contact between native and invasive species. In Chapter 1, I assess the …
-
Control of fusarium head blight in wheat: I. Evaluation of host plant resistance and fungicides II. Molecular markers associated with QTL for resistance
… essential tool for control of FHB. Breeding for resistance to FHB has become a very large part of wheat and barley breeding programs in temperate climates. Various sources of resistance have been used to develop new cultivars that have high levels of resistance. The primary objective of this …
-
Factors influencing the spread and selection of drug resistance in Human African Trypanosomiasis
A growing problem with drug resistance in Human African Trypanosomiasis has necessitated the implementation of screening programmes to monitor for its spread. This thesis describes the study of several factors that can influence the selection and propagation of drug resistance in T. brucei. Human …
Page 1 of 2