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Showing 1 to 3 of 3 for “"Rereplication"”.
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Investigation of replication fork progression and re-replication fork instability at the Drosophila follicle cell amplicons
… adjacent replication forks generate DSBs during rereplication. A single fork collision and collapse event would block all subsequent forks, suggesting efficient break repair is required for continued fork movement at the amplicons. To define the pathways responsible for maintaining re-replication …
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Meiotic Dna Re-Replication And The Recombination Checkpoint
<p>Progression through meiosis occurs through a strict sequence of events, so that one round of DNA replication precedes programmed recombination and two nuclear divisions. Cyclin dependent kinase 1 (Cdk1) is required for meiosis, and any disruption in its activity leads to meiotic defects. The …
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Mechanisms of genomic stability maintenance in fission yeast
DNA replication consists of two distinct steps: the licensing step during the G1 phase and the initiation step at the G1 to S transition point. During licensing, two inactive complexes of the replicative helicases, MCMs, are loaded onto all the potential origins of replication (ORIs), through the …