Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"Reproductive toxicity"”.
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Multigenerational Neurobehavioural and Reproductive Toxicity of Arsenic in Zebrafish (Danio rerio)
… toxicant known to affect neurological and reproductive functions, yet critical gaps remain in our understanding of its sex-specific toxicity and heritable effects across generations. This thesis investigated the multigenerational cognitive and reproductive toxicity of chronic dietary …
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Machine learning in predictive toxicology: investigating developmental and reproductive toxicity with transfer learning
The toxicity of a compound has always been a major concern in risk assessments of new products or drugs. In the field of predictive toxicology, with animal testing being phased out in some sectors, there is an urgent need for alternative methods for determining toxicity. An *in silico* method such …
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Effects of Quaternary Ammonium Disinfectants on Mouse Reproductive Function
… these compounds have been used for decades, reproductive toxicity has not been thoroughly evaluated. Extensive use of QACs results in ubiquitous human exposure to potentially toxic compounds. Reproductive toxicity of two common QACs, alkyl dimethyl benzyl ammonium chloride (ADBAC) and didecyl …
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The immediate and long-term consequences of temporary exposure during adulthood to di(2-ethylhexyl) phthalate and diisononyl phthalate on female reproduction
… that target the ovary can lead to disruptions in reproductive and overall health. The phthalate chemical family has several prominent members with endocrine disrupting capabilities. One of the most common phthalates is di(2-ethylhexyl) phthalate (DEHP), with up to 100 million pounds produced …
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Evaluating Immunotoxicity of Quaternary Ammonium Compounds
… hazards in humans, and developmental and reproductive toxicity in mice. They also cause increased secretions of proinflammatory cytokines in cell lines and vaginal inflammation in porcine models; but have not been evaluated for developmental immunotoxicity. We assessed immunotoxicity …
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Atrazine: a lively chemical journey
… certain weeds and grasses. Evidence of its neurotoxicity, hormone disruption and reproductive toxicity led the EU to ban the chemical in 2003. Despite long standing evidence of its harm, South Africa continues to use atrazine, the majority of which is imported from the EU. Drawing on South Africa …
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EFFECTS OF ANTIMICROBIAL COMPOUNDS ON EARLY LIFE STAGES OF CANADIAN FISH SPECIES
… thesis investigates the lethal and sub-lethal toxicity responses of both legacy (triclosan, TCS) and emerging (chloroxylenol, PCMX; methylisothiazolinone, MIT) antimicrobial compounds to early-life stages (ELS) of three freshwater fish species: rainbow trout (Oncorhynchus mykiss), lake trout …
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EFFECTS OF ANTIMICROBIAL COMPOUNDS ON EARLY LIFE STAGES OF CANADIAN FISH SPECIES
… thesis investigates the lethal and sub-lethal toxicity responses of both legacy (triclosan, TCS) and emerging (chloroxylenol, PCMX; methylisothiazolinone, MIT) antimicrobial compounds to early-life stages (ELS) of three freshwater fish species: rainbow trout (Oncorhynchus mykiss), lake trout …
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Developmental exposure to an environmentally relevant phthalate mixture impacts ovarian health in mice
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2027-05-01