Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 2728 for “"Replication."”.
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HQ replication
… providing Byzantine-fault-tolerant state machine replication: an agreement-based approach, e.g., BFT, that uses communication between replicas to agree on a proposed ordering of requests, and a quorum-based approach, such as Q/U, in which clients contact replicas directly to optimistically execute …
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Re-replication in the Absence of Replication Licensing Mechanisms in Drosophila Melanogaster
… once and only once per cell division. DNA replication is tightly regulated by replication licensing mechanisms which ensure that origins only initiate replication once per cell cycle. Disruption of replication licensing mechanisms may lead to re-replication and genomic instability. …
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Regulation of DNA replication and the replication initiator, DnaA, in Bacillus subtilis
DNA replication is a highly regulated process across all organisms. Improper regulation of DNA replication can be detrimental. I identified an overinitiating, conditional synthetic lethal mutant of Bacillus subtilis. I isolated suppressors of this mutant and uncovered novel genes associated with …
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Mechanisms of retroviral replication
… of viral RNA is an essential step of retroviral replication cycle. Extensive biochemical and genetic analyses suggest that majority of retroviruses employ similar mechanisms for specific RNA packaging. Better understanding of mechanisms of this process may help to develop new anti-retroviral …
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Diverse partial memory replication
… program diversity called Diverse Partial Memory Replication (DPMR), aimed at detecting memory safety errors. DPMR is an automatic compiler transformation that replicates some subset of an executable's data memory and applies one or more diversity transformations to the replica. DPMR can detect …
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Norovirus Translation and Replication
… were purified from clinical stool samples. HuNoV replication was tested in different cell types. The B-cell and intestinal organoids culture systems were validated. In addition, using organoids culture a DNA-based reverse genetic system was shown to recover infectious HuNoV. Due to the challenges …
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Replication of bovine parvovirus
… on this virus group has revealed that viral replication occurs in cycling cells only, and evidence exists that the required factor provided by cycling cells is produced during early or mid S phase. Due to this S phase dependence, parvoviruses replicate synchronously only in synchronized …
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Chromatin Dynamics During DNA Replication
… respect to promoters.<br/><br/>DNA and chromatin replication are coupled processes whereby chromatin is disrupted ahead of the replication fork and nucleosomes are rapidly assembled on the nascent DNA template. Classically it has been observed that nascent chromatin is more susceptible to …
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Static replication of exotic options
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1997.
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The dual role of lef-2 in DNA replication and late gene expression during baculovirus-replication
AcMNPV lef-2 is essential for DNA replication and is involved in expression of late and very late gene promoters. In earlier work, the isolation of a virus mutant (VLD1) deficient only in very late protein synthesis was attributed to a point mutation in lef-2. DNA replication and late protein …
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Investigation of replication fork progression and re-replication fork instability at the Drosophila follicle cell amplicons
… a powerful model system to delineate control of replication fork progression. We utilized this system to survey fork progression across diverse genomic positions from amplicons generated at ectopic genomic positions. Comparative genome hybridization (CGH) analysis reveals fork progression varies …
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Regulation of DNA replication and cellular responses to perturbations in replication in the bacterium Bacillus subtilis
… The process of genomic duplication is called DNA replication, and is closely coordinated with other processes in the cell, such as growth rate, and cell division. The mechanisms that regulate when DNA replication initiates and how cells respond to perturbations in replication are not well …
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ONCOGENE-INDUCED ALTERED DNA REPLICATION DYNAMICS
… By performing a whole genome analysis of DNA replication dynamics occurring upon oncogene activation, I discovered that oncogene activation alters DNA replication by increasing replication fork speed and fork stalling, while decreasing the frequency of replication initiation. This is …
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Parallel network protocol stacks using replication
… a powerful, but flexible model for testing the replication approach. This dissertation uses Dominoes to build a replicated network protocol system. The performance of common protocols, such as TCP/IP, is increased by multiprocessing single connections. On commodity hardware, throughput increases …
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Post-Replicative Resolution of Under-Replication
The evolutionary pressure to prevent re-replication by inactivating licensing during S phase leaves higher-eukaryotes with large genomes, such as human cells, vulnerable to replication stresses. Origins licensed in G1 must be sufficient to complete replication as new origins cannot be licensed in …
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Testing Methods of Testing Replication Success
The Replication Crisis refers to a time of doubt on the trustworthiness of the published research findings. Replicability at its simplest form is taken to mean the consistency of a finding. The crisis in confidence in research findings assumes that consistency of a finding confirms an effect and an …
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