Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"Repeated maternal separation"”.
-
Neonatal Maternal Separation and Alcohol Abuse in C57BL/6J mice: A Study of the Functional Alterations of GABAergic and GLUergic Systems and the Possible Protective Role of Esterogen
… study we investigated the effects of neonatal repeated maternal separation (RMS) on alcohol abuse in adult C57BL/6J mice and potential functional alterations of GABAergic and GLUergic systems in different brain areas. Male animals subjected to RMS consumed significantly higher amount of ethanol …
-
Behavioural, immunological, and neurobiological effects of early life stress in rats
… early life stress itself. To do this, I used the repeated maternal separation (RMS) model of chronic early life stress, and I focused particularly on those effects of possible relevance to anxiety, depression, and inflammation-related physical disease. In Chapter 3, I describe the long-term …
-
Exploring the neurobehavioural impacts of combined early life and adult stress on decision making under uncertainty
… outcomes of early life stress (ELS) using the repeated maternal separation (MS) procedure in rats. The specific hypothesis tested was that stress effects accumulate over the developmental lifespan, resulting in either stress resilience or vulnerability in adulthood. Early postnatal life is a …
-
The effect of exercise on spatial learning and hippocampal proteins in maternally separated adult rats
Repeated maternal separation (MS) has been reported to induce changes in hypothalamic-pituitary- adrenal (HPA) axis activity leading to abnormal stress responses later in life. Such alterations have also been linked to poor cognitive function. In contrast, exercise enhances cognitive function. …
-
Maternal separation in the rat : long-term effects of early life events on emotionality, drug response and neurobiology
… investigate early experiences. In the rat, maternal separation of pups in early ages have been linked to anxiety-related behavioral, endocrinological and neurochemical disruptions in the rat. The aim of the thesis was to investigate these proposed disruptions in pups exposed to repeated …
-
Network-based approaches towards understanding the emergence of neurodevelopmental disorders
… cohort in which half the animals experienced repeated maternal separation (RMS) while the other half were reared normally (Control). All animals were scanned in early adulthood (PND 63) and in later adulthood (~PND 300) following an additional adult stressor. In \textbf{Chapter 2}, I define …