Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1530 for “"Repeat"”.
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Repeat pregnancies in teenage mothers
There has been very little research into repeat pregnancy in teenage mothers. Therefore, the purpose of this study was to explore the experiences of pregnant teenage mothers who were expecting their second child. Six pregnant teenage mothers were interviewed and asked to complete a number of …
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CAG repeat expansions induce cytoplasmic RNA aggregation
Expansions of ‘CAG’ trinucleotide repeats in the genome can cause over a dozen diseases, including Huntington disease and several spinocerebellar ataxias. Short tracts of these ‘CAG’ repeats are benign; however, mutant alleles that harbor an abnormally large number of consecutive ‘CAG’ motifs can …
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Teenage mothers’ reflections of their unintended, repeat pregnancies
… on teenage girls who had experienced unintended repeat pregnancies. Through the research a deeper understanding of the meanings that female teenagers ascribe to repeat pregnancies, were sought. A sample group of teenage mothers were allowed to take a step back from their experience of the repeat …
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Identifying repeat victims: The utility of police data
Contains fulltext : 289683.pdf (Publisher’s version ) (Open Access)
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Smart Nanomaterials from Repeat Proteins and Amyloid Fibrils
… materials are amyloid fibrils and tandem repeat proteins. Amyloid fibrils are exceptionally strong, tough, highly-ordered structures that self-assemble from a wide range of simple building blocks. Meanwhile, tandem repeat proteins are a class of proteins that act as scaffolds to mediate …
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Interrogation and engineering of RAD51:BRC repeat interactions
… and interacts with RAD51 through a set of 8 BRC repeats. A BRC repeat consists of two modules, an FxxA and an LFDE module, each containing hot-spot residues that mediate binding. In this work, I set out to utilise these for the pharmacological targeting of human RAD51. First, using biophysical …
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Binge-Restrict-Repeat: The Governmentality of Eating Regimes
This study employs Michel Foucault's conceptualization of governmentality, or dispersed rationalities that seek to calculate and maximize the health of the population, to study how eating regimes of truth influence how individuals relate to their bodies and each other. Importantly, the study of …
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The impact of assessment on repeat deliberate self-harm
Deliberate self-harm is a pervasive issue that is the topic of worldwide clinical and research focus. Among the extensive research findings two salient issues emerge that provide the foundation for this study. The first is that a deliberate self-harm attempt is a significant risk factor for future …
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Study and engineering of nucleic acid-binding repeat proteins
… shown to bind their target sequences in a single repeat/base fashion. This modular recognition nature allowed researchers to rationally design these proteins for novel specificities and utilize them in diverse biotechnological applications such as genome engineering, gene expression regulation, …
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Inhibiting Protein-Protein Interactions using Rationally-designed Repeat Proteins
… of consensus-designed tetratricopeptide repeat proteins (CTPRs) make them very amenable to be rationally-designed into potential new PPI inhibitors. This study sets out to investigate whether this could be achieved through the grafting of binding peptides into the inter-repeat loops. The …
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"Injury-prone areas" Repeat Presentations for Injuries in Childhood
… host and environmental factors. Studies of repeat injuries in childhood thus provide insight into factors in the epidemiological triad predisposing children to injury. Objectives: The study objectives were to determine the proportion of children and the factors associated with repeat …
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Visitors to Mauritius - Place, perceptions and determinants of repeat visitation
… markets of Mauritius and the factors determining repeat visitation. The relationship among several constructs such as destination image, service interactions, place attachment, personal involvement, satisfaction and future behaviour is explored. Understanding these relationships, can possibly …
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A mechanism for SCA10 neurodegeneration due to intronic repeat expansion
… daily tasks. The disorder is due to an intronic repeat expansion, ATTCT, in the gene Ataxin 10. Ataxin 10 is a protein of unknown function. However, Ataxin 10 from SCA10 patient samples is known to be fully transcribed and properly spliced, resulting in a normal, but expanded transcript. The …
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Parental involvement as a tool to lower repeat suspension offenses
… in the discipline process and thereby reduce repeat discipline offense. The intern offered the opportunity for involvement to the parents of tenth grade students who received their first out-of-school suspension. The study took place during the first semester of the 2002- 2003 school year. …
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Functions of small leucine-rich repeat proteoglycans in connective tissues
… assembly, the cells secrete small leucine-rich repeat proteoglycans (SLRPs) that bind to collagen and influence its fibril formation. In this manner, fibromodulin - one of the SLRPs - can alter intermolecular cross-linking of collagen, which has long-term implications for the structural …
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Engineering Synthetic Biomolecular Condensates with Rationally-Designed Modular Repeat Proteins
… condensates based on consensus tetratricopeptide repeat (CTPR) proteins, modular folded non-globular domains, fused with low-complexity domains (LCDs), intrinsically disordered domains that drive phase separation. By systematically engineering a library of LCD-CTPR constructs sharing identical LCD …
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Short tandem repeat (STR) profile authentication via machine learning techniques
Short tandem repeat (STR) DNA profiles have multiple uses in forensic analysis, kinship identification, and human biometrics. However, as biotechnology progresses, there is a growing concern that STR profiles can be created using standard laboratory techniques such as whole genome amplification and …
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