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Showing 1 to 20 of 135 for “"Renin"”.
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Intrarenal Adrenergic Mechanisms Controlling Renin Release
… alpha- and beta-adrenoceptors in the control of renin release. In addition, the function of calcium in the adrenergic control of renin release was examined. All studies were carried out in the isolated, nonfiltering, constant-pressure perfused rabbit kidney.
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Prorenin, its maturation and the (pro)renin receptor
The renin-angiotensin system (RAS) is a key biochemical pathway controlling homeostasis and blood pressure. The initial step of the RAS is carried out by renin to produce angiotensin (Ang) I which is converted to Angll by the angiotensin-converting enzyme (ACE). Renin is synthesized as a pro-enzyme …
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An Analysis of Renin Control by Intrarenal Prostaglandins
Made available in DSpace on 2014-12-14T13:39:43Z (GMT). No. of bitstreams: 1 7811290.pdf: 6269580 bytes, checksum: 4d5e27e228173b9aaddbdbf573c7fbbb (MD5) Previous issue date: 1978
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RADIATION-INDUCED BRAIN INJURY AND THE RENIN-ANGIOTENSIN SYSTEM
… CNS has been pharmacologic suppression of the reninangiotensin system (RAS). The brain has its own intrinsic RAS which has effects beyond cardiovascular and fluid homeostasis including learning, cognition and memory. Although the pathogenesis of radiation injury remains unclear, we hypothesize …
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Modulation Of Renin Secretion By Renal Cortical Interstitial Calcium
<p>Renin is secreted from the juxtaglomerular (JG) cells of the afferent arteriole of the kidney, and is the rate-limiting enzyme of the renin-angiotensin system. Renin is quantified <i>in vivo</i> as plasma renin activity (PRA). Acutely elevating plasma calcium decreases PRA, but the mechanisms by …
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An Analysis of Renin Control During Acute Respiratory Acidosis
Made available in DSpace on 2014-12-14T13:39:39Z (GMT). No. of bitstreams: 1 7714974.pdf: 5701340 bytes, checksum: 657e55acc527ec686594ea59d445a5c0 (MD5) Previous issue date: 1977
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Studies of the renin angiotensin system in the human vasculature
The work presented in this thesis concentrates on the local generation of AII. Preliminary experiments using wire myography were performed in human resistance arteries from normal subjects, obtained by subcutaneous gluteal at biopsy. In these vessels, AI stimulated a contractile repose that was …
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The Renin-Angiotensin System in The Freshwater Turtle Pseudemys Scripta
… to verify the existence of an endogenous renin-angiotensin system in this species. It was shown that Pseudemys scripta possess renal renin, renin substrate in the plasma, angiotensin converting enzyme activity, and vascular receptors specific for angiotensin. Kinetic analyses were …
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An Analysis of Carotid Sinus Baroreceptor Control of Renin Release
Made available in DSpace on 2014-12-14T13:39:46Z (GMT). No. of bitstreams: 1 8009165.pdf: 9104467 bytes, checksum: 9d4842202a69ab2a319b3eebaf1e02bc (MD5) Previous issue date: 1979
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Investigating the role of the Renin Angiotensin System in cancer
… diseases as possible anti-cancer agents. The renin-angiotensin system (RAS) regulates blood pressure and cardiovascular homeostasis through Angiotensin Converting Enzyme-1 (ACE-1) and its homolog ACE-2. RAS has also been implicated in the progression of various cancers due to the increased …
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Die Herkunft von Renin im Rattenherz: de novo-Synthese oder Aufnahme?
… der Herkunft und Funktion von intrakardialem Renin. Untersucht wurden die Regulation der kardialen Expression des Reningens, die Möglichkeit einer Aufnahme von Renin in Herzmuskelzellen, sowie der intrakardiale Reningehalt von Sprague Dawley (SD) Ratten im Vergleich zu TGR(mREN2)27, einem …
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Factors Regulating the Intrarenal Renin-Angiotensin System and Renal Damage During Aging
The renin-angiotensin system (RAS) plays an important role in regulating blood pressure, fluid homeostasis, and it even contributes to insulin resistance. Dysfunction of this system ultimately leads to cardiovascular related diseases, such as hypertension and diabetes. Studies show that RAS …
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The Brain Renin-Angiotensin System: Biochemical Characterization and Possible Role in Hypertension
A renin-angiotensin system (RAS) endogenous to the brain has been proposed on the basis of immunochemical, biochemical and pharmacological evidence. Angiotensin II exerts potent effects in CNS tissues and appears to be involved fluid balance homestasis and blood pressure regulation. The data in …
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Alterations in the Brain Renin-Angiotensin System in a Model of Fetal Programming
… in components of the circulating and intra-renal renin-angiotensin systems (RAS) that shift the RAS to the pro-hypertensive peptide, angiotensin (Ang) II. In the brain, the Ang II AT1 receptor opposes the beneficial actions of Ang-(1-7) at the Mas receptor for control of baroreflex sensitivity and …
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Sex-Related Differences in Hypertension and Renal Injury: Role of the Renin-Angiotensin System
… rate in men than in premenopausal women. The renin-angiotensin system (RAS) contributes to the development and maintenance of hypertension. Angiotensin II (Ang II) and angiotensin-(1-7) are two peptides derived from the RAS that possess vasoconstrictive and vasodilatory actions, respectively. …
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