Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Renal nerves"”.
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Role of the renal nerves in hypertension
… clinical trials showing that ablation of the renal nerves (renal denervation; RDNX) has a significant antihypertensive effect in drug resistant patients. However, failure of the most recent sham-controlled trial has raised many questions regarding this treatment. Chief among them is whether …
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Sympathetic nervous system in the development of mild DOCA-salt hypertension
… to maintain volume homeostasis by altering the renal excretion of salt and water in response to changes in arterial pressure. But there is also compelling evidence for a role of the central nervous system in long-term regulation of arterial pressure, primarily by modulating sympathetic nerve …
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Interaction Of Afferent Renal Nerve Activity And Il-1R Signaling In Hypertension
Renal denervation was recently approved by the FDA for the treatment of hypertension, but the mechanism by which it reduces blood pressure is unclear. Studies of patients who have received the treatment have shown a variety of off-target improvements in conditions associated with sympathetic …
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Factors Regulating the Intrarenal Renin-Angiotensin System and Renal Damage During Aging
… not entirely known. The activation of the intrarenal RAS and onset of renal dysfunction occurs over the same time span as many of the features of the MetS, while the systemic RAS declines. This suggests that suppression of the intrarenal RAS may be partly responsible for the salutary effects of …
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Sympathetic neural control of renal blood flow
Renal sympathetic nerve activity (RSNA) plays an important role in the control of renal hemodynamics and function. It achieves this control by changing the mean levels of activity and/or changing the power of the distinct frequencies that comprise this mean activity. My studies, presented in four …
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Renal blood flow in the conscious, unrestrained rat
… is to test the hypothesis that the rate of renal blood flow remains constant under normal physiological conditions. Methods were developed for long term studies of renal blood flow (using the Doppler flow probe) and blood pressure in the conscious unrestrained rat. Special care was taken to …
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The role of renal afferent signalling in chronic intermittent hypoxia-induced sympathoexcitation and hypertension
… baroreceptors. Blunted baroreflex control of renal sympathetic nerve activity (RSNA) was revealed in hypertension models that involve renal inflammation. Suppression of inflammation restored the normal baroreflex control of RSNA in some of these models, suggesting that renal inflammation …
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Renal failure and the neural control of the kidney
Renal failure (RF) is associated with an over activation of the sympathetic nervous system. The aim of this thesis was to investigate the hypothesis that as the kidney progresses into RF there is an inappropriate and sustained activation of renal afferent nerves which results in a dysregulation of …