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Showing 1 to 20 of 138 for “"Renal Function"”.
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Modelling Renal Function in Drug Pharmacokinetics
… are eliminated from the body by the kidneys. Renal function is an important covariate to describe variability in drug clearance (CL) of renally eliminated drugs. This thesis explores the use of renal function in population pharmacokinetic (PK) and pharmacodynamic (PD) models, and its influence …
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Importance of renal function in cardiac surgery
… In this work we studied different aspects of renal function after cardiac surgery. The first paper shows in a retrsospective study of 5261patients, when preoperative estimated glomerular filtration (eGFR) rate by s-creatinine and preoperative hemoglobin is entered into a Cox analysis together …
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Renal function during profound hypothermia in the dog
… it was suggested that, as a member of the Renal-Metabolic Group of the Department of Medicine, I co-operate wit the surgeons, in a study of renal function during profound hypothermia in the dog. This thesis details our progress and results.
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The relationship between reduced renal function and cardiovascular disease
… examines the relationship between measures of renal function and cardiovascular disease (CVD) in patients with hypertension (the NORDIL study) and in the healthy population (Malmö Diet and Cancer Study, MDC) and whether antihypertensive treatment response and the risk of CVD is affected by …
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Renal Function in Relation to Exercise and Thermal Environment
Made available in DSpace on 2014-12-11T22:22:09Z (GMT). No. of bitstreams: 1 7114817.pdf: 3057438 bytes, checksum: 63f392da60bf0f668777cafa622c2135 (MD5) Previous issue date: 1970
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Statistical analysis of renal function in patients with cancer
… approaches and analyses for the filtration function of the kidney in patients with cancer, using widely available clinical data. The filtration function of the kidney is reported as the glomerular filtration rate (GFR). Many clinical decisions, for example dose calculations for chemotherapy …
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Development of a Mathematical Model of Renal Function for Clinical Application
… to calculate total and differential effective renal plasma flows which are compared to standard PAH clearance tests. A blood-to-urine flow index, defined in this research using these parameters, and a cortex-to-medulla transit is also used to evaluate various renal diseases surgically induced …
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Renogram Image Characteristics and the Reproducibility of Differential Renal Function Measurement
Aim The reproducibility of differential renal function (DRF) estimates on 99mTc-mercaptoacetyltriglycine (99m Tc-MAG3) is good in the majority of children. There is however a small but important group with poor reproducibility which, if not recognized, could affect clinical decision making. Some …
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Effect of Fenoldopam on Renal Function in Normal Dogs Following Nephrotomy
… To evaluate the effect of fenoldopam on renal function in normal dogs subjected to bisection nephrotomy. In addition, effects of bisection nephrotomy on renal function in normal dogs were evaluated. Study Design: Controlled, randomized, blinded experiment Sample Population: Sixteen mixed …
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Low molecular mass proteins as markers for renal function and dialysis efficiency
Kidney disease is a growing problem in the whole world. It is important to find these patients in an early state of the disease because then they can be treated and dialysis treatment can be avoided. To measure the glomerular filtration rate (GFR) an invasive technigue is used. In this thesis an …
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The Pharmacokinetics of Oxytetracycline in Dogs With Normal and Impaired Renal Function
A renal failure model was developed in 29 dogs by electrocoagulation of one renal cortex and contralateral nephrectomy to enable the adjustment of therapeutic drug doses in relation to renal function. The magnitude of renal dysfunction, defined by the percentage of normal glomerular filtration rate …
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The Effect of Nephrotomy on Renal Function and Morphology in Normal Cats
… To assess effects of bisection nephrotomy on renal function, size, and morphology in cats over a period of 12 weeks. Study Design: Controlled, randomized, blinded experiment. Sample Population: Ten adult female cats. Methods: Glomerular filtration rate (GFR), as determined by quantitative …
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The Acute And Chronic Effects Of Resveratrol On Renal Function And Blood Pressure
… the acute and chronic effects of resveratrol on renal function and blood pressure. We hypothesized that resveratrol would act as a renal vasodilator through a nitric oxide-dependent mechanism. In our acute studies, we found an intravenous bolus of resveratrol influenced changes in renal …
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Influence of Pregnancy on Renal Function and Feturs in Women with Underlying Renal Disease
… of pregnancy on the natural course of maternal renal disease continues to be debated. There have been many reports published in Western countries on this issue; however there is limited data in Korea. In this study, we investigated the effect of pregnancy on renal function in women with …
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Do percutaneous nephrostomies for malignant obstructive uropathy improve renal function six months post intervention?
… ureteric obstruction and associated impaired renal function, which can be managed by performing percutaneous nephrostomy (PCN) tube insertion. Nephrostomy tubes are associated with prolonged hospital stay which affects quality of life. The main objective of this study was to assess the changes …
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Mechanisms of Improved Renal Function Following Normothermic Ex-vivo Kidney Perfusion Preservation of Grafts Severely Damaged by Prolonged Warm Ischemia
… perfusion (NEVKP) is an emerging technique for renal graft preservation. We investigated whether NEVKP could improve early function of severely injured donation-after-cardiovascular death (DCD) grafts to reduce the incidence of delayed graft function (DGF). First, we develop a large-animal model …
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