Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 16 of 16 for “"Relocalisation"”.
-
Localisation and Resilience at the local level: the case of Transition Town Totnes
… the Transition approach, resilience and economic relocalisation, with the aim of analysing whether and how they can be implemented in a locality based on the Transition approach, and assessing what socio-economic and community-related structures would be necessary to implement such a process. The …
-
Perspective d'un développement rural durable : le cas des Hmongs du Laos
… que les stratégies de sédentarisation sans relocalisation et avec relocalisation sur l'initiative soit personnelle soit gouvernementale ont fait leurs preuves. Des changements dans les modes de production et de vie ont non seulement permis une meilleure utilisation du sol, une augmentation …
-
Nutraceutical modulation of lipotoxicity and the development of a tool to monitor palmitate induced sub-cellular dysfunction.
… 6), a protocol for monitoring the sub-cellular relocalisation of proteins and lipids is developed using the Localisation of organelle proteins by isotopic tagging (LOPIT) technique. Organelles are separated based on their densities and proteomic and lipidomic LCMS open-profiling is used to …
-
Identification and characterisation of novel interactors of surfactant protein C
… I found that many induced misprocessing and relocalisation of SFTPC-WT to the plasma membrane, phenocopying the I73T mutation. I undertook further validation of top hits in a novel CRISPR interference AT2 organoid model. I also undertook an exploration of the biology of MPZL1, a poorly …
-
Bone Morphogenetic Protein Signalling in Adult Lung Epithelial Cells
… was found to be modulated with the apparent relocalisation of the BMP receptor, BMPR-IA, to the nucleus of airway epithelial cells. Furthermore, this nuclear localisation was recapitulated in normal primary MAECs co-cultured with eosinophils or stimulated with eosinophil cationic proteins. …
-
Regulation of sphingosine kinase 1 oncogenic signalling by calcium and integrin binding proteins
… SK1. CIB2 blocked agonist- and oncogene-induced relocalisation of SK1 to the plasma membrane and the associated pro-survival and pro-oncogenic signalling. In further examining the potential role of CIB2 as a tumour suppressor, I found that CIB2 was significantly downregulated in ovarian cancer …
-
Subzelluläre Lokalisation des Y-box-Proteins-1 (YB-1) in Mesangialzellen und Charakterisierung der dafür verantwortlichen Proteindomänen
… restitution was associated with YB-1 relocalisation to the nucleus. In the course of different other models of rat glomerular disease YB-1 remained nuclear. In the second part of the study we examined YB-1 localisation in the in vitro model of proliferating rat mesangial cells, which …
-
L’implication de la signalisation des Bmps dans le maintien de l’homéostasie de la muqueuse intestinale et colique et dans les pathologies digestives.
… villositaire, une hyper migration et une relocalisation cytoplasmique de la E-cadhérine dans les cellules épithéliales. Cette étude permet de démontrer l’importance de la signalisation des Bmps dans les maladies inflammatoires intestinales, puisque les défauts occasionnés par la perte de …
-
Nouveau rôle pour la ferriréductase Frp1 dans l’acquisition de l’hème par la voie Shu1-dépendante chez la levure Schizosaccharomyces pombe
… de manière similaire à Shu1, et que cette relocalisation dépend du système ESCRT et requiert l’ubiquitinylation de Frp1 au niveau du résidu lysine 365. Dans l’ensemble, le modèle que nous proposons suggère que l’hème exogène est d’abord capturé par le récepteur Shu1 localisé à la membrane …
-
Cellular principles of Xenopus appendage regeneration
… inflammatory myeloid lineage cells prevent ROCs' relocalisation. These findings suggest a regeneration-permissive environment is also required to regenerate an appendage. Finally, I focused on Xenopus limb regeneration by comparing limb amputation responses of various regeneration-competency …
-
An investigation of the interaction between the immune system GTPase GIMAP6 and an autophagy gene 8 homologue GABARAPL2
… with GABARAPL2 fail to display a similar relocalisation. Finally, recent research has demonstrated that members of the GIMAP family can homo- and hetero-dimerise. I have shown that GIMAP6 can interact with itself and intriguingly, also shows a specific interaction with GIMAP7. Contrary to …
-
Oberflächenpotentialverteilungen durch galvanostatische 3-D-Rastermessungen
… of the measurement procedure in two steps, a relocalisation of the topographical data and the potential distribution is required. This is the main restriction for the detection of very small surface irregularities. During pilot tests with plane copper samples the main parameters of …
-
Regulators of autophagy in Leishmania major
… purified antibodies. ATG8A exhibited a dramatic relocalisation to punctate structures under starvation conditions, suggestive of a specific role for ATG8A in starvation induced autophagy. Although ATG8 and ATG8A both participate in a response to starvation, they differed in their sensitivity to …
-
The mechanisms of aquaporin expression and translocation in cerebral pathologies
… against hypoxia induced cytotoxic oedema. This relocalisation of AQP4 was shown to involve mechanisms dependent on the transient receptor potential vanilloid 4 (TRPV4) channels, calcium and calmodulin activation. Investigation into the role of AQP expression and regulation in temporal lobe …
-
Valorisation du savoir local pour une cogestion conservatoire de l'arganeraie marocaine
… de l’agdal, la structuration du marché et la relocalisation de la plus-value (IGP argane), la promotion du tourisme rural, la réalisation d’actions d’accompagnement. Par ailleurs, cette stratégie doit s’inscrire dans le cadre d’un développement local plus global pour pouvoir prendre en compte …
-
Degrowth at a Global Scale? Geographies of Chile¿s Fruit Production and Export between Extractivism and Socio-Ecological Transformation
L'abstract è presente nell'allegato / the abstract is in the attachment