Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 47 for “"Relationship study"”.
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A Structure-Activity Relationship Study of Dihydroajoenes as Anti-Cancer Agents
… double bond, in which the intention was to study the influence of removing the double bond on biological activity and metabolic stability, since ajoenes are unstable in blood. A divergent synthetic route to 6 new dihydroajoene analogues has been developed in which a phenolic hydroxyl group …
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Process-Structure-Property Relationship Study of Selective Laser Melting using Molecular Dynamics
… properties. The process-structure-property relationship of the SLM process is not well-understood. In the process-structure study, a quasi-2D model of Micro-Selective Laser Melting process using molecular dynamics is developed to investigate the localized melting and solidification of a …
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Isolation, Synthesis and Structure-Activity Relationship Study of Anticancer and Antimalarial Agents from Natural Products
… sesquiterpenoids, and a structure-activity relationship (SAR) studies on the antiplasmodial anthroquinones.
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Improving Potency and Oral Bioavailability of Spinster Homolog 2 (Spns2) Inhibitor: A Structure-Activity Relationship Study
In healthy individuals, the autoimmune system is the body's natural defense against foreign materials and organisms. The main tools utilized for this defense mechanism are immune cells. However, in patients suffering from autoimmune diseases, the autoimmune system is overactive resulting in its …
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Psychology observed within every romantic relationship study: Testing equality of parameters across diverse gender and sexual identities
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-02-04 without embargo terms
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A Relationship Study of Assistant Principals' Reported Self-Efficacy and Organizational Efficacy Levels Based Upon Job Preparation Experiences in One K-12 Public School District
The purpose of this study was to investigate self-efficacy and organizational efficacy as reported by assistant principals for relationships to their job preparation experiences in one K-12 public school district. Bandura defined self-efficacy as "]belief in one's capabilities to organize and …
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A Structure-Activity Relationship Study with Isoquinolinone Compounds and Stromal Antigen 2 Mutant Ewing’s Sarcoma Cells and Synthesis of Small Molecules for Anticancer Activity Through TEAD Palmitoylation Inhibition
… will be focused on the structure-activity relationship study with isoquinolinone compounds, and the second on the synthetic approach to small molecules that inhibit the growth of cancer cells through the Hippo signaling pathway. Ewing’s sarcoma is the second most commonly diagnosed …
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The social exchange/reciprocity relationship between employers and employees and the role of trust in the exchange process
This thesis comprises of two studies. Study 1 is a replication and extension of a previous study investigating employer a?? employee social exchange/reciprocity relationship. Study 2 examines the role of dispositional trust (generalized trust) and relational trust (trust in supervisor) in the …
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Development of Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spns2 for the Treatment of Multiple Sclerosis
Sphingosine-1-phosphate (S1P) is an amino-alcohol signaling molecule produced from the intracellular phosphorylation of the lipid sphingosine. Despite possessing several identified intracellular targets, the predominant signaling functionality of S1P is derived from its activation of membrane-bound …
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Seeking interdependence: Commitment desirability and the initiation and maintenance of close relationships
… extent to which they believe that a committed relationship is desirable for them. The current research offers and examines the concept of commitment desirability, defined as the subjective desire to be involved in a committed romantic relationship. In six studies, the present research developed …
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Developing Sphingosine-1-Phosphate (Spns2) Inhibitors for the Treatment of Multiple Sclerosis
Autoimmune diseases are caused when a person's immune system attacks its own healthy cells. In a person with multiple sclerosis, their immune system becomes sensitized to the myelin sheath that covers their neurons in the central nervous system. This results in the degradation of the myelin sheath …
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Public perception of the effectiveness of public input in the parks and recreation planning process at the Boone County fairgrounds
… by their input. The research design for this study was a cross sectional, relationship study to determine the relationships between perceived effectiveness of public input, access and availability of information, understanding of the process, setting and timing,fairness of the process and …
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Gender and counterproductive work behavior (CWB): a personality-based explanatory model
… do women (Ng, Feldman, & Lam, 2016). The present study proposes an explanatory model for the CWB gender gap, using personality traits (narcissism, sadism, agreeableness, conscientiousness, and emotional intelligence) and sex role orientation (agency and communion) to explain the gap. Study 1 uses …
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Assessing "you," "me," and "us": A comprehensive measure of relational schemas
Expectations about interpersonal relationships have been shown to be highly influential in terms of behavior, goals, affect, and interpersonal outcomes. However, one important conceptualization of these expectations, the relational schema, has been understudied, largely due to the lack of a clear, …
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Synthesis of Sphaeropsidin a Derivatives in a Search for Compounds Active Against Drug-Resistance Cancer
… anticancer activity, its SAR (Structure-Activity Relationship) study has suggested that the activity can be enhanced by modifying the double bond at C15-C16. This double bond can be modified by crossmetathesis reaction of SphA with an alkene-containing compounds. Previously, a similar study was …
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Multivariate time series clustering using kernel variant multi-way principal component analysis
… two simulation studies were conducted. The first study has the same mean structure groups with error structures which are combinations of three different auto-correlation levels and three different cross-correlation levels. Two different mean structure groups with nine error structures were …
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Permeating the wall: Transmitting knowledge remittances as a strategy for health information campaigns in The Republic of Moldova
… (TAM2), two studies evaluated the remittance relationship. Study 1, an exploratory online survey (n = 15), indicated that Moldovan immigrants living in the United States and Canada that have a generally positive attitude towards capital and knowledge remittances will tend to perceive the …
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Probing complex ionic dynamics on the nanoscale via energy discovery platforms
… dynamics. The comprehensive structure-property relationship study of these materials not only showcases the feasibility of energy discovery platforms in complex ionic dynamics study on the nanoscale, but also facilitate material and device design with better performance and reliability.
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Chemical Mutagenesis for the Modulation and Study of Protein Function and Dysfunction within Alzheimer’s Disease
… mutagenesis to enable a structure-activity relationship study on a single-domain antibody (SdAb) beyond the 20 canonical AAs. The starting SdAb was designed to target the Amyloid-b peptide (Ab) and has a nascent ability to inhibit its aggregation, a key pathological process in AD. Utilizing …
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