Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Regional Heterogeneity"”.
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Postnatal specialization of astrocyte regional heterogeneity in the mammalian brain and improved tools for studying glia
… regions, the developmental trajectory of this regional heterogeneity requires further systematic study. Chapter 1 of this thesis provides a detailed literature review on the development of astrocyte regional heterogeneity. To address existing knowledge gaps, we used single-nucleus RNA …
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Examining Implicit Price Variation for Lake Water Quality
… to a concern that these models may overlook regional heterogeneity in water-quality preferences. We estimate scaled-up hedonic models comprised of multiple states and individual states and investigate how observations from subregions can differ. We find that the scaled-up model results are …
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A Computational Model of Inert Gas Mixing in the Lung
… tests, but they cannot be used to bridge to regional ventilation data acquired using contrast-enhanced \textit{in vivo} imaging. The goal of this thesis is to develop a mathematical model for predicting inert gas transport and mixing in the lung, such that the model includes the important …
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Mechanical Signals for Compensatory Lung Growth Assessed by High Resolution Computed Tomography
… lungs. HRCT was used to quantitatively assess regional distribution of lung volume and density gradients among lobes of the lung in order to follow the expansion of remaining lobes following lung resection with a high degree of anatomical precision, and to determine the relationships between …
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Fibulin-2 Stabilizes Tumor Extracellular Matrix and Drives Malignant Progression of Lung Adenocarcinoma
… during periods of uncontrolled growth, creating regional heterogeneity and torsional stress. How tumors maintain ECM integrity in the face of dynamic biophysical forces is still largely unclear. This study addresses these deficiencies using mouse models of human lung adenocarcinoma. Spontaneous …
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ESSAYS ON MONETARY ECONOMICS
… for the 50 U.S. states from year 1977 to 2005. Regional heterogeneity as well as the cointegration and cross-section correlation properties of panel data are considered in great detail. Contrary to previous studies in the field, we adopt panel data techniques with nonstationary and cointegrated …
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Mutation of Polaris, an Intraflagellar Transport Protein, Shortens Neuronal Cilia
… necessary in order to maintain neuronal cilia. Regional heterogeneity in the effect of this gene mutation on neuronal cilia suggests that the functions of some brain regions might be more compromised than others.
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Assessment of subsidized shared transport services on mobility patterns: Evidence and Lessons from cellphone mobility data
… insignificant effects overall, although notable regional heterogeneity was observed. Furthermore, the ride-hailing mode under the MOD Project was more effective in increasing POI visitation than the micro-transit mode of Metro Micro. These results highlight the critical role of service …
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Recessions, Recoveries and Regional Resilience: an econometric perspective
… and empirical approaches dealing with regional evolution in order to identify recent developments and extensions incorporating spatial econometrics techniques. Chapter II investigates transient and permanent asymmetric effects of national-wide recessions across Italian regions during …
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Engineered Heart Tissues for Advanced Disease Modeling
… by addressing its throughput and lack of regional heterogeneity, two limitations of the system that exist in its current form. To increase the throughput, we designed a miniaturized EHT (mEHT) platform that is compatible with a standard 96-well culture plate. The mEHTs generated on this …
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Climate-induced trends in global riverine water discharge and suspended sediment dynamics in the 21st century
… change in the 21st century. Despite substantial regional heterogeneity, a global net increase is projected for both river discharge and sediment flux in the 21st century under all RCP scenarios. Increases are larger and more variable with increasing levels of GHG concentrations in the atmosphere. …
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Biohybrid Neural Interfaces: Exploring the Role of Regional Astroglia in Neuronal Integration and Functionality
… diverse impacts on these neurons due to their regional heterogeneity, however, this aspect is less often addressed in current BNI research. In the first chapter, we conducted a thorough scoping review of the developments and challenges facing current BNIs. During the developmental phase of our …
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Investigating the representation of smoke and its implications for air quality and climate
… that global climate models need to represent regional heterogeneity in absorption properties. We also show that a 1-day whitening lifetime of brown carbon matches observations well and substantially decreases the warming contribution of biomass burning. Chapter 4 expands the model …
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Spatiotemporal Distribution of Siberian Wildfires and Impacts from Meteorological and Climatic Factors
… climatic drivers are of great importance for the regional environment and global climate change. Using fire data from Global Fire Emissions Database version 5 (GFED5), surface fuel datasets, atmospheric reanalysis data, and multiple climate indices during 2001 to 2020, this study systematically …
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In search of the incidence of the corporate tax on employment and wages: evidence from U.S. state tax reforms
… corporate tax policies. Moreover, I document a regional heterogeneity and notice a slowdown in state tax changes after the Federal Reform Act of 1986. These findings matter for the empirics of corporate tax incidence, which is increasingly concerned with the endogeneity between tax reforms and …
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Spatiotemporal lifecycle assessment of the light-duty vehicle fleet of United States
… This thesis presents my work on the first regionally explicit (county-level) lifecycle assessment of two technologies directed at mitigating the GHG emissions of light-duty vehicles in the U.S. - lightweighting and electrification. Regional differences in climate, electric grid mix, and …
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Modeling and forecasting international credit risk : the case of sovereign loans
… question of whether controlling for unobserved heterogeneity is important for predicting debt crises and explores a pervasive inference problem in Early Warning Systems (EWSs). Second, it addresses the development of an `optimal' EWS for sovereign debt crises that accommodates the decision …
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A genome-wide, single-cell analysis of vascular smooth muscle cell plasticity
… heterogeneous. I hypothesised that functional heterogeneity of VSMCs in disease may originate from VSMC heterogeneity in healthy arteries. In the first part of this thesis I explored the regional heterogeneity of VSMCs originating from different parts of the mouse aorta, as well as …
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Essays in Empirical Microeconomics
… a better understanding of the determinants of regional wage differentials and employment offers insights into: the roles played by local production, consumption and city structures; the standard of living enjoyed by workers with different human capitals; and policy recommendations for the …
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Essays in labor economics and panel data analysis
… to address concerns related to unobserved heterogeneity. Recent work has shown that the negative effects of minimum wages on employment found using traditional methods are sensitive to the inclusion of controls for regional heterogeneity and selection of states that experience minimum wage …
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