Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Reference memory"”.
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The Effects of Early Postnatal PCP Administration on Performance in Locomotor Activity, Reference Memory, and Working Memory Tasks in C57BL/6 Mice
… pups were assessed in locomotor activity, a reference memory task in the Morris water maze, and a spatial delayed alternation task in the T-maze. Additionally, pups were subjected to a pharmacological challenge with PCP in the delayed alternation task. In males, No significant differences …
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Stereological Analysis of Oligodendrocyte Progenitor Cells In the Adult Mouse Brain
… used stereology to establish whether extensive reference memory training and system-wide administration of GABAergic agonists and antagonists could influence the proliferation and differentiation of adult OPCs, as well as the prevalence of OPC-neuron pairs. Analysis of the effects of reference …
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Effects of perinatal dietary choline supplementation on learning and memory in the adult rat
… choline supplementation on learning and memory in the adult rat were investigated. Subjects were 36 experimentally naive female and male Long-Evans rats. A .05M/litre solution of saccharin containing either 0or 5m1/litre of 70% choline chloride was administered via drinking water to …
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Molecular alterations of AMPA receptors and their effects on hippocampus dependent tasks
… tasks, ranging from neophobia to spatial reference memory, in a variety of genetically modified mice. Studies using GluR-A knock-out (GluR-A-/-) mice showed that GluR-A containing AMPA receptors are required for working memory, strengthened by those findings that expression of a transgenic …
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Environmental- and Ethanol-Induced Effects on Reference and Short-Term Memory in the Rat
… dendritic branching, and enhance learning and memory. Recently, the preventative effects of enrichment have been considered, specifically relating to drugs of abuse (Solinas, Thiret, Chauvet, & Jaber 2010; Stairs & Bardo 2009). This series of studies examined the effects of daily EE on …
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COGNITIVE TRAINING AND FUNCTIONAL RECOVERY IN AN AGED MODEL OF TRAUMATIC BRAIN INJURY
… were again evaluated in the MWM using both reference and working memory paradigms on the task. There was a significant benefit of the cognitive training in the injured animals, but only on the reference memory task. It also appears that cognitive ability before injury does influence the …
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The Role of Nogo-A in Memory and Neuronal Plasticity in the Aged Rodent Brain
… immunotherapy improves performance on a spatial memory task after a sensorimotor cortical stroke in aged rats. We found that rats with ischemic stroke and treated with anti-Nogo-A immunotherapy performed better on the reference memory portion of the Morris water maze than control antibody treated …
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Glutamate Dysregulation in a TauP301L Mouse Model of Alzheimer's Disease
… and TauP301L mice in the DG and CA1. However, memory-impaired TauP301L mice exhibited a 7-fold increase in glutamate release in the CA3 region of the hippocampus, and spatial reference memory errors correlated with potassium-evoked glutamate release in the CA3. These data suggest a possible …
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Phenomenon of Homelessness
… central perspective, but as the very locus of reference, memory, imagination, and integration." Phenomenology comes from the Greek word 'Phainomenon' meaning "that which appears" and "logos" meaning study. The thesis studies 'homelessness', a social phenomenon characterized by a physical …
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ENVIRONMENTAL GEOMETRY IN FISHES AND TORTOISES: EFFECT OF LANDMARKS, BEHAVIOURAL METHODOLOGIES, AND SENSORY CHANNELS ON SPATIAL REORIENTATION
… driven by spontaneous behaviour (“social-cued memory task”) and the other by learning processes (“rewarded exit task”); 3) the involvement of extra-visual sensory channels in visual transparency conditions, and motion patterns. The present Thesis applied behavioural assessments and analyses to …
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Characterising hippocampal replay in the APP<sup>NL-G-F</sup> mouse model of Alzheimer’s disease
… generally replay is also held to play a role in memory retrieval, navigation, and likely planning. Consistent with these multiple roles, replay disruption negatively impacts performance on memory related tasks. The hippocampus and associated structures are known to be among the first to exhibit …
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Pharmacological modulation of learning and memory in mice and zebrafish: Implications for Alzheimer’s disease animal models
Learning and memory impairments are the clinical manifestations of several neurodegenerative disorders including Alzheimer’s disease (AD), the most common form of dementia affecting millions of people worldwide. Current AD treatments target cognitive decline or failure and provide only minor …