Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Rectal administration"”.
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The efficacy and safety of artesunate suppositories in combination with other antimalarials in the treatment of severe malaria in Sudan.
… has been carried out following oral and rectal administration of 200mg sodium artesunate. Since artesunate was rapidly eliminated from the plasma, the pharmacokinetic evaluation was determined from the metabolite dihydroartemisinin rather than artesunate. The major pharmacokinetic …
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Anti-malaria drug treatment in Vietnam
… the treatment of severe malaria in adults. The rectal administration of artemisinin would obviollsly constitute a useful therapeutic advance, in comparing with parenteral drugs such as artemether and artesunate, particularly in areas where parenteral administration is …
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Two-Part Reactive Formulations for Intranasal Delivery of Benzodiazepines
… commonly used being intravenous lorazepam or rectal diazepam. Despite the effectiveness of these drugs, the delivery routes are not ideal for first-line, outpatient treatments. A skilled caregiver must be present to administer drugs intravenously, and the social stigma associated with rectal …
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BIOMEDICAL, IMMUNOLOGICALS AND EPIDEMIOLOGICAL STUDIES ON LEISHMANIA
… delivery: IgG and neutralizing response after rectal administration of LeCoVax-2, a candidate vaccine against COVID-1G. [pubblicato in: Pharmacological Research] Questo studio esplora il potenziale dei cloni ricombinanti di L. tarentolae come veicolo per la somministrazione mucosale di vaccini, …
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Development of amoxicillin suppositories and in vitro/ in vivo evaluations
Background: Rectal drug delivery is a potential route of administration, especially for children in low- and middle-income countries, where pneumonia is a leading cause of childhood death. An inexpensive, accessible, stable rectal formulation suitable for an outpatient setting could help reduce …