Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Reconsolidation"”.
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A role for reconsolidation in the testing effect
… occur has been put forth based on the idea of reconsolidation. Following results in the neuroscience of animal learning and human learning, the reconsolidation hypothesis assumes the act of retrieval renders the original memory for the retrieved event more malleable than a re-study opportunity. …
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Extinction of Threat Memory via Reconsolidation Interference: A Behavioral Intervention Meta-Analysis
… memories can be altered through a process called reconsolidation interference. Consolidated memories are dynamic: reminders of previous experiences prompt the reactivation of a previously-encoded memory; destabilization of the memory opens it to update. While a memory is updating, it is labile. If …
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An assessment of reconsolidation blockade to disrupt memories relevant to psychiatric disorders
… memory trace. Blockade of the resultant process, reconsolidation, with NMDA receptor antagonists or protein synthesis inhibition can lead to a decrease in subsequent memory expression. This may offer a potential tool for the treatment of psychiatric disorders characterised by maladaptive memories, …
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Effects of behavioral tasks on memory reconsolidation and trauma-related symptoms : a randomized clinical trial
… tasks (e.g., Tetris) may disrupt the reconsolidation of fear memories and may have clinical utility for the treatment of PTSD. The overarching objective of this dissertation was to investigate the effects of a visuospatial task on memory reconsolidation and trauma-related symptoms in …
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Investigating Spatial Memory Reconsolidation in Rats: Memory Updating, Effects of Aging, and Hippocampal Network Activity
… disrupted, or updated via a process of "reconsolidation". This dissertation is comprised of three experimental studies in rats aimed at investigating previously unexamined aspects of this dynamic memory process. The first study assessed whether spatial memories learned under …
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Estimating the effectiveness of stone columns in mitigating post-liquefaction settlement using Plaxis 2D
… loose sand, it causes post-liquefaction reconsolidation that can potentially yield substantial damage to the structure. To build resilient infrastructure, it is paramount to estimate these settlements as well as introduce soil reinforcement techniques to mitigate associated risks. …
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The precision of initial context fear memory encoding determines the behavioural, cognitive and molecular changes that occur following recall
… further experience, and the destabilization-reconsolidation sequence, a process by which memories become destabilized, strengthened, and re-consolidated following reinforcement. However, while there are hints that animals may be able to change the composition of their contextual memories …
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Optimization of fracturing fluid to increase shale gas production
… process. Combined with confining pressure, the reconsolidation happened inside samples. Through more experiments the mechanism of reconsolidation has been discovered that both confining pressure and temperature are necessary for gelling in fracture. Perspective on the whole formation, well logs …
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Entraver la reconsolidation synaptique à l’aide de propranolol pour traiter la douleur nociplastique : études de faisabilité randomisées contrôlées par placebo chez des participants atteints de lombalgie chronique et de fibromyalgie
… post-traumatique (TSPT). La thérapie de la reconsolidation (TR), utilisée pour traiter le TSPT, vise à réactiver les synapses qui sous-tendent les réactions d’alarme excessives et à bloquer leur reconsolidation à l’aide de propranolol. Objectifs : L’objectif principal de la thèse était …
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Performance of drains in earthquake-induced liquefaction mitigation under new and existing buildings
… simulation of the drain behaviour during soil reconsolidation. The influence of the foundation bearing pressure as an important factor in the performance of the drain arrangements was observed during and after the shaking, in the evaluation of a simplified arrangement of vertical drains under …
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Optogenetic investigation of normal and pathological rhythms in the hippocampal formation
… sleep, and thought to be important for memory reconsolidation. Using optogenetic light ramp stimuli in transgenic mice, I found that gradual depolarization of CA1 pyramidal cells (mimicking CA3 sharp-wave input) is sufficient to induce fast gamma and sharp-wave ripple-like high frequency …
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An experimental study of hydraulic fracture and erosion
… pressure and examined the effects of subsequent reconsolidation time on refracturing pressures. For the analysis of these tests results, simple criteria for hydraulic fracturing are proposed. The test results suggest that hydraulic fracturing for undrained conditions occurs when the drained …
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The Effect of Rapamycin Paired with Traumatic Memory Activation on Cognitive Performance in Veterans Diagnosed with PTSD
… targets the protein kinase mTOR, can prevent the reconsolidation of a reactivated fear memory, thereby reducing its emotional strength at a neurochemical level. The aim of the current study was to determine if pairing rapamycin with traumatic memory reactivation in male veterans with …
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Molecular and epigenetic mechanisms of fear memory
… DSBs in contextual fear memory consolidation and reconsolidation, respectively. Additionally, we behaviorally and molecularly characterized IFL and compared it to directly acquired fear subjects. We found that contextual fear conditioning changed the expression of 86 genes in the hippocampus one …
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Targeting AMPA Receptor Modulation during Early Life Adversity: A Mediator for Threat Associated Memories
… retain a threat response, suggesting consistent reconsolidation of memories in juveniles is needed for the sustainment of threat memories. The need for consistent reconsolidation of memories is a developmental feature not present in the adult rodent brain. Studies focusing on the natural …
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A psychological analysis of the effects of memory retrieval prior to extinction on the reacquisition of a conditioned fear association
The successful reduction of fear is the aim of clinicians treating people with anxiety disorders such as post-traumatic stress disorder or phobias. Existing treatments for these conditions, however, require many treatment sessions and are prone to relapse. A new technique, first demonstrated in …
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EXAMINING THE INFLUENCE OF TIME AND REPETITION ON RECENT AND REMOTE AUTOBIOGRAPHICAL MEMORY RETRIEVAL USING fMRI
Repetition and the passage of time influence the consolidation of long-term episodic memories. The experiments presented here have explored the influence of repetition on recent and remote autobiographical memories both behaviorally with regard to qualitative and quantitative measures of content, …