Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 47 for “"Recombination events"”.
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Human common fragile site FRA16D flexibility peak is not a strong mitotic: Recombination hotspot in <i>saccharomyces cerevisiae</i>
… flexibility peak from FRA16D can induce mitotic recombination events that lead to loss of heterozygosity (LOH) on chromosome III in <em>Saccharomyces cerevisiae</em>. Two experimental yeast strains containing flexibility peak Flex1-(AT)15 from FRA16D were compared to a control strain lacking the …
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Investigation of natural genetic modifiers of meiotic crossover frequency in Arabidopsis thaliana
Meiotic recombination, known as crossover, is a vital mechanism for generating genetic diversity in sexually reproducing populations. Recombination events are non-uniform across the genome, due to a variety of influences including chromatin structure, DNA-sequence, epigenetic marks and interference …
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The Role of Epigenetics in the Regulation of Meiotic Recombination in Triticum aestivum and Arabidopsis thaliana
… is an outcome of the process of meiotic recombination, a cascading series of events during which homologous chromosomes undergo pairing and reciprocal exchange of genetic information. During meiotic recombination, meiotic DSB formation and crossover localization is negative correlated in …
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Transposon Tn5 mutagenesis in Pseudomonas aeruginosa: a study of Beta-lactamase expression
… P. aeruginosa were generally unsuccessful and recombination events were observed in most transconjugants tested. Spot-mating conjugation was capable of introducing pRTG1 into P. aeruginosa albeit at very low frequencies. Analysis of the resulting transconjugant plasmids showed pRTG1 was …
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Erfassung von mutagenen und rekombinogenen Effekten durch die Hefe 'Saccharomyces cerevisiae'
… quantitative registration of different genetic events possible. With the help of the URA3 gene in the strain HAN forward mutations can be detected. The close coupling of the URA3 gene with the ADE2 locus and the kanMX4 cassette makes it possible to detect beside point mutations also more …
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The broken genome: Merging cutting edge technologies for a molecular understanding of the Flock House virus defective interfering particle.
… been truncated or rearranged by non-homologous recombination. While not encoding for functional viruses, they can be amplified and co-passaged with the wild-type virus, effectively parasitizing the normal viral machinery. Some defective RNAs can replicate so successfully so as to subdue the …
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The Evolution of Recombination Landscapes and Mechanisms in Drosophila in Light of Intragenomic Conflict
Sex and recombination are ubiquitous across the vast majority of life on earth. In eukaryotes, recombination during meiosis yields new variation that selection acts upon and, thus, facilitates evolution. However, meiosis provides an arena for manipulation and exploitation by selfish genetic …
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An HMM-based boundary-flexible model of human haplotype variation
… assume that block boundaries are areas of free recombination. In reality, haplotypes break up when they recombine, and many past recombination events are predicted to occur at sites of occasional recombination. Thus, the genuine unit of shared genetic variation should often cross block …
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The effect of pathogens on plant genome stability
… stability. Tabacco plants transgenic for a recombination construct exhibited reduced genome stability upon infection with a virulent pathogen (tobacco mosaic virus). The reduced genome stability manifested as an increase in recombination events in the transgene. Such increases were observed …
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Shared Haplotype Length Regression and Its Application
… Assuming the new allele does not become extinct, recombination events at each generation will gradually shorten the haplotype among those with the allele. Thus, on average, relatively recent alleles should reside on longer haplotypes compared to random haplotypes not under positive selection. My …
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FIV-FCA and FIV-PCO Reverse Transcriptases: Expression, Purification and Activity Comparison
… virulence in their natural hosts. Additionally, recombination in FIV infested cats is common but there is no evidence for recombination in endemic cougar infections. The reverse transciptase (RT) encoded by FIV plays a key role in the virus life cycle and is central to both evolutionary rates and …
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FIV-FCA and FIV-PCO Reverse Transcriptases: Expression, Purification and Activity Comparison
… virulence in their natural hosts. Additionally, recombination in FIV infested cats is common but there is no evidence for recombination in endemic cougar infections. The reverse transciptase (RT) encoded by FIV plays a key role in the virus life cycle and is central to both evolutionary rates and …
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Studies at the hemochromatosis (HFE) locus : gene conversions, haplotypes, and association analysis
… (HFE) to investigate the impact of meiotic recombination events upon haplotype structure in this region. First we identified crossover hotspots in order to define the boundaries of haplotype blocks in this locus. We then found that gene conversion events play a significant role in shaping …
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Linkage mapping and genetic analysis of Trypanosoma brucei
… in the location of regions of high and low recombination frequency (hot and cold spots) in the two maps. The genetic linkage map presented here is the first available for T.b.gambiense and can now be utilised to find the location within the genome of genes responsible for phenotypic traits …
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Diversity and virulence of the genus Cronobacter revealed by multilocus sequence typing (MLST) and comparative genomic analysis
… and C. dublinensis including evidence of recombination events between species. An evolutionary analysis revealed the Cronobacter genus to have evolved 45-68 million years ago, during the period of evolution of flowering plants. The MLSA was also used in a polyphasic study for the formal …
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ADVANCED MATERIALS: PREPARATION, STUDY AND OPTIMIZATION OF THIN FILM FOR OPTO-ELECTRONIC DEVICE
… and electrons from the cathode; some of the recombination events between the holes and electrons result in electroluminescence (EL). The first part of this PhD Thesis surveyed different aspect in OLED technology that are currently under debate. In particular chapter 2 is devoted to the study, …
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Niche-adaptive evolution in Campylobacter jejuni
… porcine ST403CC may show evidence of increased recombination with C. coli, however this was not observed. Six ST403CC isolates of porcine origin were subjected to phenotype testing and whole genome sequencing; these isolates were capable of invasion in vitro, and were revealed both to have …
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Studio dei meccanismi molecolari coinvolti nel determinismo sintomatologico di piante infette da virus e virus-satelliti
… due to both genomic mutations and possible recombination events among different strains. In the second case, we studied the influence of Y-sat (CaRNA5 satellite) on symptoms of CMV (Cucumber mosaic virus) in Nicotiana benthamiana plants: strong yellowing appearance instead of simple mosaic. …
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Outer-core emission spectroscopy of the heavy alkaline-earth metals
… format, the set of symmetry allowed recombination events is determined. The initial core-excited configuration is found to involve a strongly local, d-like charge which is spin polarized parallel to the core. Because the optical transition between this configuration and the ground …
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