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Showing 1 to 2 of 2 for “"Recombination Mediator"”.

  1. Mechanism of regulation of human RAD51 recombinase through post translational modifications & mediator proteins

    … plays an important role in homologous genetic recombination (HR), an essential DNA metabolic process used by cells to faithfully repair the most deleterious forms of DNA damage and maintain genomic integrity. RAD51 along with its bacterial counterpart RecA, bacteriophage UvsX and archaeal RadA …

    uiuc Repository record for Mechanism of regulation of human RAD51 recombinase through post translational modifications & mediator proteins (opens in a new tab)

  2. Mechanisms of human RAD51 regulation by RAD52 and BRCA2

    … (ss)DNA substrates to mediate homologous DNA recombination (HR) and replication fork protection, processes vital in human cells for the maintenance of genome stability. RAD51 assembly is controlled by two key mediator proteins in eukaryotic organisms – the tumour suppressor, BRCA2, and RAD52. …

    cambridge Repository record for Mechanisms of human RAD51 regulation by RAD52 and BRCA2 (opens in a new tab)