Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Receptors, Notch"”.
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Notch signaling pathway in human vascular smooth muscle cell differentiation
Notch receptor-ligand interactions are a highly conserved mechanism, originally described in developmental studies using Drosophilae, that regulate inter-cell communication and dictate, in part, vascular smooth muscle cell (VSMC) fate in response to mechanical stimuli. VSMC differentiation is a …
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The Role of Notch1 in Adult Hippocampal Neurogenesis and Function
… underlying mechanisms are still poorly defined. Notch1 is a master regulator of developmental neurogenesis, yet its role in adult hippocampal neurogenesis is unclear. To test the hypothesis that cell-intrinsic Notch1 is critical to both basal and exercise-induced SGZ neurogenesis, we generated …
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Spatial-Temporal Regulation of the Atonal Homolog 1 Gene
Controlled spatio-temporal expression of atonal homolog 1 is necessary for the correct development of the cerebellar granule cells, the dorsal interneuron 1 population, gut goblet cells and the cochlear and vestibular hair cells of mice. The purpose of these studies was to determine how atonal …