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Showing 1 to 4 of 4 for “"Receptors, Nicotinic"”.

  1. Role of M3 muscarinic receptor in regulation of immunity to infectious pathogens

    … cholinergic signaling via acetylcholine and its receptors has emerged as an important regulator of immunity. Acetylcholine binds to and signals through two types of receptors; nicotinic and muscarinic receptors. Studies have shown that signaling through nicotinic receptors, particularly the α7 …

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  2. Cholinergic Control of Cortical Circuit Activity

    … was reliant on the engagement of both nicotinic and muscarinic acetylcholine receptors. Nicotinic receptors mediated transient suppression by acting in the superficial cortical layers, while muscarinic receptors mediated prolonged suppression in layer 4. In agreement, we found …

    uthsc Repository record for Cholinergic Control of Cortical Circuit Activity (opens in a new tab)

  3. Structure and Function of the Alpha3Beta4 Nicotinic Acetylcholine Receptor

    Nicotinic acetylcholine receptors are pentameric ligand-gated ion channels that are essential for the proper function of the central and peripheral nervous systems. The α3β4 subtype is highly expressed in the autonomic ganglia, where it contributes to signal transduction from the central nervous …

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  4. Understanding the Atomic-Scale Mechanisms of the Human [alpha]4[beta]2 Nicotinic Acetylcholine Receptor

    Nicotinic acetylcholine receptors are pentameric ligand-gated ion channels. These receptors are present in the central and peripheral nervous systems where they mediate fast synaptic transmission by allowing the flux of cations through the plasma membrane. The heteropentameric α4β2 subtype is the …

    utswmed Repository record for Understanding the Atomic-Scale Mechanisms of the Human [alpha]4[beta]2 Nicotinic Acetylcholine Receptor (opens in a new tab)