Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Receptors, Metabotropic Glutamate"”.
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An Examination of the Mechanisms of Neocortical Network Excitability in a Mouse Model of Fragile X Syndrome
… levels. Pharmacological or genetic reduction of metabotropic glutamate receptor 5 (mGluR5) signaling reduces UP state duration in the Fmr1 KO to normal levels, suggesting a potential therapy for Fragile X patients. These data characterize the novel phenotype of hyperexcitable cortical circuitry …
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A Study on an FMRP-Mediated Translational Switch in the MGluR-Triggered Translation of Arc and Synaptic Plasticity
The group 1 metabotropic glutamate receptor (mGluR)-stimulated protein synthesis and long-term synaptic depression (mGluR-LTD) are altered in a mouse model of Fragile X Syndrome, Fmr1 knockout (KO) mouse. Fmr1 encodes the Fragile X mental retardation protein (FMRP), a dendritic RNA-binding protein …
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Recettori purinergici ionotropi e i loro ruoli nella neuroinfiammazione mediata dalla microglia
… simile nella neuroinfiammazione e il recettore metabotropico del glutammato mGlu5 è espresso in queste cellule, nella prima parte di questo progetto è stata studiata un'interazione tra questi due sottotipi di recettori. Inoltre, poiché è noto che gli steroidi neuroattivi svolgono un ruolo …