Global ETD Search

THE FUNCTIONAL REGULATION OF FCRN EXPRESSION AND FCRN-MEDIATED ANTIGEN PRESENTATION

Liu, Xindong2009

The neonatal Fc receptor for IgG (FcRn), a major histocompatibility complex (MHC) class I-related molecule, plays an important role in IgG transport and protection. The transport of IgG across epithelial and endothelial barriers and the IgG homeostasis maintained by FcRn contributes to the …

maryland Repository record for THE FUNCTIONAL REGULATION OF FCRN EXPRESSION AND FCRN-MEDIATED ANTIGEN PRESENTATION (opens in a new tab)

Engineering aglycosylated antibody variants with immune effector functions

Sazinsky, Stephen L. (Stephen Lael)Massachusetts Institute of Technology2009

… - mediated by the interaction of the conserved Fc regions of the antibody with the Fc gamma receptors (Fc[gamma]Rs) on immune cells - is critical to the efficacy of several. This thesis describes the engineering of antibody Fc domain interactions with Fc[gamma]Rs, using the' yeast S. cerevisiae. …

mit Repository record for Engineering aglycosylated antibody variants with immune effector functions (opens in a new tab)

C-reactive protein mediated Fc-gamma-receptor signal transduction is enhanced by low density lipoprotein in human macrophages

Li, KefeiUniversität Ulm

ulm-diss Repository record for C-reactive protein mediated Fc-gamma-receptor signal transduction is enhanced by low density lipoprotein in human macrophages (opens in a new tab)