Global ETD Search

C-reactive protein mediated Fc-gamma-receptor signal transduction is enhanced by low density lipoprotein in human macrophages

Li, KefeiUniversität Ulm

ulm-diss Repository record for C-reactive protein mediated Fc-gamma-receptor signal transduction is enhanced by low density lipoprotein in human macrophages (opens in a new tab)

THE FUNCTIONAL REGULATION OF FCRN EXPRESSION AND FCRN-MEDIATED ANTIGEN PRESENTATION

Liu, Xindong2009

The neonatal Fc receptor for IgG (FcRn), a major histocompatibility complex (MHC) class I-related molecule, plays an important role in IgG transport and protection. The transport of IgG across epithelial and endothelial barriers and the IgG homeostasis maintained by FcRn contributes to the …

maryland Repository record for THE FUNCTIONAL REGULATION OF FCRN EXPRESSION AND FCRN-MEDIATED ANTIGEN PRESENTATION (opens in a new tab)

The effect of manipulating apoptotic cell uptake on their immunogenicity

Attfield, Kathrine ElizabethUniversity of Southampton2009

… second which re-directed apoptotic cells through Fc? receptors and conferred enhanced phagocytosis by both macrophages and immature dendritic cells (DN-MFG-E8-Fc) in a dose-dependent manner.<br/>Cross-presentation of cell-associated antigen by bone marrow-derived dendritic cells (BMDCs) was …

soton Repository record for The effect of manipulating apoptotic cell uptake on their immunogenicity (opens in a new tab)

Engineering aglycosylated antibody variants with immune effector functions

Sazinsky, Stephen L. (Stephen Lael)Massachusetts Institute of Technology2009

… - mediated by the interaction of the conserved Fc regions of the antibody with the Fc gamma receptors (Fc[gamma]Rs) on immune cells - is critical to the efficacy of several. This thesis describes the engineering of antibody Fc domain interactions with Fc[gamma]Rs, using the' yeast S. cerevisiae. …

mit Repository record for Engineering aglycosylated antibody variants with immune effector functions (opens in a new tab)

Using Advanced Fluorescence Microscopy to Analyze Intracellular Trafficking of FcRn In Live Cells

Gan, Zhuo2013

The file named "GanZhou.pdf" is the primary dissertation file. All other files ("*.mov") are supplemental files and may be viewed individually.

utswmed Repository record for Using Advanced Fluorescence Microscopy to Analyze Intracellular Trafficking of FcRn In Live Cells (opens in a new tab)

Modeling steric effects in antibody aggregation using rule-based methods

Hoard, Brittany

… initiated by the aggregation of antigens and IgE-FcεRI antibody-receptor complexes. Computational modeling of antibody- antigen aggregate formation as well as the size and structure of these aggregates is an important tool for greater understanding of the allergic response. In addition, the …

unm Repository record for Modeling steric effects in antibody aggregation using rule-based methods (opens in a new tab)

Targeting the Neonatal Fc Receptor, FcRn, to Treat Autoimmunity and Elucidation of Sites of FcRn Function

Challa, Dilip Kumar2020

The neonatal Fc receptor, FcRn, is expressed in many different cell types and serves several functions, some of which are cell type-specific. A function common to most cell types that express this receptor is salvage of IgG from cellular degradation which is responsible for the long in vivo …

utswmed Repository record for Targeting the Neonatal Fc Receptor, FcRn, to Treat Autoimmunity and Elucidation of Sites of FcRn Function (opens in a new tab)