Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Receptors, Antigen, T-Cell"”.
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Re-Designing Cancer Immunotherapy to Enhance Anti-Tumor Immunity
… we designed a novel local mesenchymal stromal cell (MSC) based immunotherapy to study the immune tumor microenvironment (TME), and optimized radiotherapy delivery with cGAMP and systemic α-PD-L1 immunotherapies. Using MSC, we delivered various forms of anti-CD3 and/or co-signals to explore …
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Modulation of CD8+ T Cell Function by Beta2-Adrenergic Receptor Signaling
… upon stimulation, which can modulate immune cell function primarily through the beta2-adrenergic receptor (ADRB2). Our previous work has demonstrated that various subsets of CD8+ T cells have differential expression of the ADRB2 transcript. The role of ADRB2 signaling on the differentiation …
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Sympathetic Neural Control of Inflammation by ADRB2-Mediated IL-10 Secretion
… nervous system to communicate with immune cells through adrenergic receptors (ADR). Although, the effects of adrenergic signaling has been studied in multiple cell types, its role in modulation of innate immune cells is relatively unknown. Here, I demonstrate a novel role for the beta2-ADR …
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Modulation of T Lymphocytes by Tumor-Released Survivin
… intense interaction between normal and malignant cells. Factors and cell types within this environment can play a crucial role in the progression or regression of the tumor. Of primary interest are tumor-infiltrating T lymphocytes, which have been shown to have a key role in modifying the dynamics …