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Showing 1 to 2 of 2 for “"Receptor-Interacting Protein Serine-Threonine Kinases"”.

  1. Characterization of a Novel Signaling Motif in the CD3 ε Subunit of the T Cell Receptor

    The T cell receptor (TCR) complex consists of the ligand-binding α/β heterodimer as well as four associated signaling chains (CD3 γ, δ, ε, and ζ). Each of the CD3 subunits contains one or more copies of a signaling motif termed an immunoreceptor tyrosine-based activation motif (ITAM). …

    utswmed Repository record for Characterization of a Novel Signaling Motif in the CD3 ε Subunit of the T Cell Receptor (opens in a new tab)

  2. The Role of CK1 in Necroptosis and Confirmation of Amyloid-Like Fibers in Necroptosis Using 2D SDD-AGE

    … complex called the necrosome, which contains receptor-interacting protein kinase 1 and 3 (RIPK1, RIPK3) and mixed-lineage kinase domain-like protein (MLKL). Phosphorylation of human RIPK3 at serine 227 (S227) has been shown to be required for downstream MLKL binding and necroptosis …

    utswmed Repository record for The Role of CK1 in Necroptosis and Confirmation of Amyloid-Like Fibers in Necroptosis Using 2D SDD-AGE (opens in a new tab)