Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Receptor c-kit"”.
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Investigating the isoform-specific role of phosphoinositide 3- kinase p110delta
… of tyrosine kinases or G protein-coupled receptors, respectively. The mammalian catalytic subunits of class IA PI3Ks are p110α, p110β and p110δ. PI3Ks are involved in multiple cellular processes, and deregulation of PI3K signalling pathways have been linked to a number of diseases such as …
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Human-Mouse Neural Crest Chimeras as a Novel Model for Human Melanocyte Biology in Development and Disease
… environment via expression of a single mouse receptor (c-Kit) on human donor cells to rescue an evolutionarily divergent ligand/receptor interaction required for melanoblast proliferation and survival. We find that this extends the persistence of human NCCs, but does not lead to postnatal …
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Transcriptional profile of c-kit positive cardiac stem-progenitor cells (c-kitpos eCSCs) isolated from the four chambers of the adult human heart
… cells (eCSCs). They express the stem cell factor receptor c-kit, are distributed throughout the myocardium, are clonogenic, self-renewing and multi-potent, in that they differentiate into the 3 main cardiac lineages; cardiomyocytes, smooth muscle and endothelial cells in vitro and in vivo. The …
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The study of the role of mast cells in malignant pleural effusion
… nuclear factor-κΒ activation, respectively. cKIT inhibitor imatinib mesylate was effective against effusion development, indicating that mast cell-dependent effusion formation is actionable.