Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Receptor TLR4"”.
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A Dual Investigation of Questions in Drug Addiction: Exploring the Role of Neuroinflammation in Opioid Withdrawal and A Novel Measure of Reward-Seeking Behavior in Rodents
… mouse model lacking the key microglia immune receptor TLR4 was used to determine the involvement of this protein in the molecular and behavioral responses to opioid withdrawal, in particular those related to negative emotions. Although technological advances in behavioral testing techniques …
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Suppression of pro-inflammatory signalling pathways by sulforaphane
… of cysteine residues 609 and 246 within the LPS receptor, TLR4 under non-reducing conditions, to reduce the levels of inflammatory mediators that are produced in response to LPS. The anti-inflammatory effect of SF was not restricted to the TLR4 pathway, and significant reductions were observed in …
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Examination of the effect of weaning stress on the physiological and molecular regulation of immune function in circulating bovine leukocytes
… of inflammatory cytokines, the glucocorticoid receptor, TLR4, CD62L and Fas, than weaning calves next to the dam. Additionally, a far more potent inflammatory response, at the transcriptomic level, was reported to occur in weaned and housed calves compared with housed calves, indicating that …
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The role of lipid A in the virulence of ESKAPE pathogens
… and humans. The canonical membrane-bound lipid A receptor, TLR4, and TRAM-TRIF are responsible for K. pneumoniae lipid A remodelling. PhoPQ plays a prominent role in governing the lipid A modifications found intracellularly. These findings shed insight into the complex intracellular pathogenesis …