Global ETD Search
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Showing 1 to 2 of 2 for “"Receptor, Platelet-Derived Growth Factor alpha"”.
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PDGFRalpha Signaling Requirements in the Development of Tissues Derived From Sclerotome and Dermatome
The Platelet-Derived Growth Factor Receptors (PDGFR) play roles in the development of multiple mesenchymal cell types. Upon ligand binding, the receptors signal through a number of intracellular signaling molecules and elicit many cellular responses including migration, proliferation, and …
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Mesothelial and Mural Cell Contribution to Vascular Development through PDGF Signaling
… of mural cells has not been clearly defined. The platelet derived growth factor beta (PDGFR beta) is essential for mural cell recruitment and expansion. Deletion of PDGFR beta leads to perinatal lethality resulting from vascular defects attributed to severe decreases in mural cells. PDGFR beta is …