Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Real-world evidence"”.
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REPRODUCTION AND CHILDBEARING HEALTH: REAL-WORLD EVIDENCE FROM ADMINISTRATIVE DATABASES
Introduction. Over the last three decades, especially in high-income countries, reproduction has undergone significant changes, influenced by a combination of social, economic, technological, and cultural factors. The delay in the age at which individuals and couples decide to have children is one …
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Underexposed areas in psoriasis care: insights from real-world evidence
Contains fulltext : 332890.pdf (Publisher’s version ) (Closed access)
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A DATA-DRIVEN PRIORITIZATION ALGORITHM FOR MEDICATION REVIEW IN OLDER ADULTS: FROM REAL-WORLD EVIDENCE TO CLINICAL PRACTICE
… a growing challenge for healthcare systems worldwide, given the rising multimorbidity and polypharmacy in aging populations. Inappropriate pharmacological regimens not only increase the risk of adverse drug reactions and hospitalizations but also contribute to excessive healthcare costs and …
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Enhancing the Reliability of Real-World Evidence and Clinical Decision-Making: Robust, Calibrated, and Uncertainty-Aware Methods for Observational Healthcare Research
Real-world data (RWD) has become instrumental in clinical and public health research, providing opportunities for more generalizable and practical insights compared to traditional randomized controlled trials (RCTs). Nevertheless, observational studies inherently encounter critical challenges, such …
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Διαδικασιες για την εγκριση και τη διεξαγωγη κλινικων μελετων απο τις ρυθμιστικες αρχες
… όπως η τηλεϊατρική, τα wearables και τα real-world evidence. Οι ρυθμιστικές αρχές ανταποκρίθηκαν με κατευθυντήριες γραμμές που διευκολύνουν την ενσωμάτωση των DCTs, ενώ παράλληλα αναδύονται τεχνολογίες όπως η τεχνητή νοημοσύνη και το blockchain για τη διασφάλιση της συμμόρφωσης, της …
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Comparing Healthcare Resource Utilization and Costs in HFPEF patients using SGLT2-inhibitor Combination Treatments: A Retrospective Claims Analysis
… (ARNIs) as adjunctive therapy. However, real-world evidence comparing healthcare resource utilization (HCRU) and costs between these combination therapies remains limited. Methods: We conducted a retrospective cohort study using the Merative™ MarketScan® commercial and Medicare databases …
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The Use of Oncology Electronic Health Record Databases to Assess the Effectiveness of Breast Cancer Treatment
… patients seen in routine care that reflect real-world practice patterns and treatment adherence. Historically, pharmacoepidemiology research in the oncology setting has been limited, mainly due to poor capture of important confounding factors in real-world data sources (e.g., tumor grade, …
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Medicinal Chemistry of Cannabis and Cannabinoids
… Through this thesis, we report significant real-world evidence for the case that cannabis and cannabis extracts behave as complex mixtures of physiologically active molecules, whereby their effects on receptors vary significantly with chemotype and in turn reflects their chemical …
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EXCEED: enabling and excelling equitable evidence generation for digital health.
… and healthcare has given rise to a new era of evidence-based medicine. Digital health technologies (DHTs), defined in 2022 as “systems that use computing platforms, connectivity, software, and/or sensors for healthcare and related uses,” have become rapidly incorporated across medical …
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Empowering RCT with Multi-site Multi-source RWD: a Statistical Learning Perspective
… and the scope of inference. In contrast, real-world data (RWD), such as electronic health records (EHRs), capture broader and more representative populations but introduce challenges including bias, missing data, and the lack of randomization. Integrating these data sources effectively can …
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Κατευθυντήριες οδηγίες για την αξιοποίηση των RWD/RWE στην αξιολόγηση τεχνολογιών υγείας / Guidelines for RWD/RWE in the health technology assessment
… με τη χρήση των "Δεδομένων Πραγματικού Κόσμου" (Real-World Data - RWD) και "Αποδεικτικών Στοιχείων Πραγματικού Κόσμου" (Real-World Evidence - RWE) στην Αξιολόγηση Τεχνολογιών Υγείας (Health Technology Assessment - HTA). Μέσα από μια συστηματική βιβλιογραφική ανασκόπηση των κατευθυντήριων οδηγιών …
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A social identity approach to understanding physical activity.
… activity settings. Study 1 provided initial real-world evidence that forming a strong social identity as a member of a particular exercise group (i.e., as a parkrunner) is associated with greater group-relevant participation, more positive experiences of participation, and broad …
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Influenza Antivirals in Adults: Analyzing Usage Trends, GI Safety, and Cardiovascular Risk Reduction
… severe influenza-related complications, their real-world utilization patterns, safety profiles, and broader health effects are not fully understood. Specifically, knowledge gaps remain concerning antiviral prescribing among high-risk populations, the potential risk of gastrointestinal (GI) …
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Αξιολόγηση της αποτελεσματικότητας και ασφάλειας των βιο-ομοειδών της ριτουξιμάμπης σε ασθενείς με ρευματικά νοσήματα
… Τα διαθέσιμα δεδομένα πραγματικών συνθηκών (real-world evidence) σχετικά με την αποτελεσματικότητα και την ασφάλεια των διαθέσιμων βιοομοειδών της ριτουξιμάμπης για την θεραπεία των ρευματικών νοσημάτων παραμένουν περιορισμένα. Σκοπός Στόχος της παρούσας μελέτης ήταν η σύγκριση της …
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Strategies for sustainable livestock production in Brazil and the European Union
… could reduce the land use of EU pork (20% of world production) by one fifth, potentially saving 1.8 million hectares of agricultural land. This would also reduce 12/14 other assessed environmental impacts and deliver economic savings for pig farmers, as swill (cooked food losses) costs 40-60% …
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Real-world Pharmacological Anticoagulation and Clinical Outcomes of Venous Thromboembolism in Adults with Sickle Cell Disease
… complication. However, there have been limited real-world studies on VTE in SCD patients. This work aims to provide a comprehensive assessment of the risk factors and treatment of VTE in adults with SCD by using longitudinal real-world data. First, a retrospective cohort study on 30-day …