Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Read mismapping"”.
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Development of An In Silico Kir Genotyping Algorithm and Its Application to Population and Cancer Immunogenetic Analyses
… sequencing technologies that map short reads to a reference genome exhibit high rates of read mismapping in regions containing loci that are homologous, polymorphic, and variable in content. I developed a novel approach for rescuing KIR genotyping function from sequence read alignment …
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A Quantitative Exploration of Causes of False Positive Single Nucleotide Polymorphisms in Next-Generation Sequencing Data
… approach to SNP discovery is based on mapping reads to a reference sequence. Apart from sequencing errors, which vary in pattern and rate depending on the sequencing platform, the short read lengths that prevail in NGS, together with the repetitive nature of the genomes of many organisms, can …