Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"RdRPs"”.
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Role of basic and hydrophobic residues in the poliovirus polymerase elongation complex and the structure of a coxsackievirus polymerase elongation complex
… RNA. To efficiently replicate the genome, RdRPs must form a stable and processive elongation complex (EC) by binding RNA, incorporating the first templating nucleotide, and undergoing a necessary conformational. Upon completion of these steps that comprise initiation, the newly formed EC is …
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The Mechanism of RNA Interference in Neurospora
… analyses using strains lacking all potential RdRps suggested that unlike in C.elegans and Arabidopsis, the amplification of secondary dsRNA or siRNA is largely absent in Neurospora. The search for potential regulatory mechanisms of RNAi components in Neurospora led to the identification of a …
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RNAi em Colletotrichum lindemuthianum: caracterização das proteínas-chave e desafios para a aplicação
… (DCL) e três RNA polimerases dependentes de RNA (RdRPs). Dentre essas, ClAGO2, ClRdRP2 e ClRdRP3 foram descritas pela primeira vez na espécie. Todas as proteínas apresentaram domínios altamente conservados, e a análise filogenética indica que os genes que as codificam foram mantidos nos genomas, …
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De Novo Initiated RNA Synthesis by the Hepatitis C Virus RNA-dependent RNA Polymerase
… the overall mechanism of RNA synthesis in viral RdRps but also open new avenues for developing HCV polymerase inhibitors.
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Functional analysis of the cellular RNA-directed RNA polymerase (RdRP) in higher plants
The cellular RNA-directed RNA polymerase 2 (RdRP^2) full-length cDNA was successfully cloned and its authentic sequence has been deduced from the Lycopersicon esculentum cultivar Rentita (tomato). Insights into the possible biological function of the RdRP^2 were achieved by down-regulating …