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Showing 1 to 3 of 3 for “"RbpA"”.

  1. Structural and Functional Studies of Mycobacterial General Transcription Factors RbpA and CarD

    … and its dependence on two transcription factors, RbpA and CarD, which are essential in the pathogen Mycobacteria tuberculosis (Mtb). In this thesis, I report the structural and biochemical characterization of RbpA and describe how it works synergistically with CarD to compensate for the unstable …

    rockefeller Repository record for Structural and Functional Studies of Mycobacterial General Transcription Factors RbpA and CarD (opens in a new tab)

  2. Cryo-EM Studies of Bacterial RNA Polymerase

    … the actinobacteria general transcription factor RbpA and an upstream promoter DNA fork (us-fork) in the presence and absence of Fdx to identify the structural determinants of Fdx binding to RNAP. The results show that Fdx acts like a doorstop fo jam the RNAP clamp module in an open conformation. …

    rockefeller Repository record for Cryo-EM Studies of Bacterial RNA Polymerase (opens in a new tab)

  3. Inquiries into the Mycobacterial Caseinolytic Protease System

    … Mtb model organism M. smegmatis (Msmeg). RbpA, an essential transcription factor, was highly enriched and found to be regulated post-translationally by ClpC1 through recognition of an N-terminal degron sequence. Such hits contribute to the short list of documented mycobacterial Clp …

    rockefeller Repository record for Inquiries into the Mycobacterial Caseinolytic Protease System (opens in a new tab)