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Showing 1 to 20 of 51 for “"Rats as laboratory animals"”.
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L-NAME- Induced Hypertension in the WKY and BHR Rat
… Wistar-Kyoto (WKY) and borderline hypertensive rats (BHR) was studied by inhibiting the synthesis of nitric oxide, an endothelial-derived relaxing factor. The BHR is genetically predisposed to developing hypertension in response to chronic exposure to environmental stress. After normalizing for …
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A Study of the Leptospiral Carrier State of Rats
… "icterohaerrorrhagiae". This investigation was done to determine if the Des Moines wild rat population was infected with "L. icterohaemorrhagiae". The virulence of any isolate was to be tested in laboratory hamsters and rats. Procedure. Wild Des Moines rats were captured and euthanized, …
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Blood vascular pattern to and through the gastrocnemius of the sedentary male rat
Thesis (M.A.)--Michigan State University. Dept. of Physical Education, College of Education, 1968
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The Effects of Prenatally Induced Hypothyroidism of the Neural Development and Problem Solving Ability of Maturing Hypothyroid Rats
The problem. The problem was to yield neonate rats hypothyroid by treating pregnant female rats with propylthiouracil (PTU), and then to evaluate the problem solving ability and the changes in the brain of the hypothyroid offspring. Procedure. Three 8-day sperm-positive female rats were given PTU …
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Investigations into the Actions of Vasopressin Histamine, Isoproterenol, Phentolamine, Phenylephrine, and Propronalol on Flow Through Perfused Rat Livers
… any intrahepatic actions of the drugs employed as presinusoidal or postsinusoidal and to identify any antagonism of the drugs to others. Procedure. Livers were excised and perfused at a constant rate through the portal vein with different drugs and at different concentrations. Absolute pressure …
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Effects of Early Cirrhosis on Hepatic Vascular Resistance in the Rat
The Problem. Increased vascular resistance in the liver is a common symptom of established cirrhosis of the liver. This investigation measured changes in resistance during induction of cirrhosis, to determine whether the increase in vascular resistance might be part of the mechanism by which …
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Patterning of Behavior in a Concurrent Variable-Interval Schedule as a Function of the Changeover Delay
The problem. The present study was conducted to determine the temporal placement of licking in a concurrent schedule of reinforcement and to see how various changeover delays affect the temporal placement of licking. Procedure. Rats were trained to press a lever for food. Food was made available by …
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The Matching Law and Schedule: Induced Drinking
The problem. The present study was conducted to replicate the findings of a previous study and to determine if the matching law would apply to different categories of schedule-induced drinking. Procedure. Rats were taught to press a lever for food. Food was made available by a concurrent …
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The Effects of Conditions of Homogenization on the Contents of Nuclei Isolated From Rat Liver
… from 05 to 40. Nuclei were isolated, counted, measured and analyzed for nucleic acid and protein contents. Finding. It was found that the amount of homogenization had a very little effect on the contents of the isolated nuclei. Conclusion. Further homogenization has no effect on protein content …
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Effects of Thyroxine and Propylthiouracil Treatment of Young Male Sprague-Dawley Rats on Potassium-Induced Contraction of Thoracic Aorta
… treatment of young male Sprague-Dawley rats on aortic ring contraction induced by increasing potassium concentrations. Procedure. Three groups (N=6) of thirty-day-old male Sprague-Dawley rats were treated for nineteen days with thyroxine (200 micrograms by injection), propylthiouracil …
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