Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Raphé"”.
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The Effect of Electrical Stimulation of the Dorsal Raphe Nucleus on Local Cerebral Glucose Metabolism and Epileptogenesis in the Rat
<p>Anatomic connections between the dorsal raphé and the hippocampus have been described in the literature; however, the understanding of the functional importance of these connections is not complete. In these studies the "functional" raphé-hippocampal pathway was elucidated first by the …
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Exploring the effects of 5-HT2A and AMPA receptors on brain 5-HT via a mechanism-based pharmacodynamic model
… on the control mechanisms involved in the dorsal raphé nucleus (DRN) which is the serotonergic control center located in the midbrain. We hypothesized that activation 5-HT 2A receptor in PFC would increase serotonin levels by an AMPA-dependent mechanism in both DRN and PFC. Enhancement of the 5-HT …
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The Role of the Serotonergic Neurotransmitter System in the Development and Treatment of Affective Disorders
… neuron type. Many transcripts were enriched in raphé samples, including both known markers of serotonergic neurons, and novel genes, most of which could be confirmed from by in situ hybridization data from the Allen Brain Atlas. In postnatal fluoxetine treated mice, we report alterations at the …
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Exploring the effect of alpha2 receptor on brain 5-HT via a mechanism-based pharmacodynamic model
… had inhibition effect on 5-HT level in dorsal raphé nucleus (DRN), Prefrontal cortex (PFC) and Hippocampus (HP) with the dual reuptake inhibition. The present study was undertaken to explore the effect of BRL44408 (α 2 receptor antagonist) on 5-HT level in rat PFC, DRN and HP under dual …
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Alterations in adult behavior as a result of early life manipulations
… within specific subregions of the dorsal raphé nucleus (DRN) of prenatally stressed males. The number of c-Fos immunoreactive serotonergic neurons did not differ in response to acute restraint, suggesting similar levels of activation, and therefore similar CORT response. However, the …
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3,4-Diaminopyridin evozierte Freisetzung von Neurotransmittern aus Hirnschnitten von Ratten
Das Modell der 3,4-DAP evozierten Transmitterfreisetzung wurde in dieser Arbeit zur Freisetzung von Serotonin, Noradrenalin und Acetylcholin im Hippocampus und Kortex der Ratte angewandt. Vor der Stimulation wurden die bei den jeweiligen Experimenten zu testenden Substanzen zugesetzt. Deren Wirkung …