Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Randomised controlled clinical trial"”.
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A comparison of two saliva substitutes in the management of xerostomia during radiotherapy for cancer of the head and neck
… for cancer of the head and neck. This crossover randomised controlled clinical trial was carried out on twenty-five patients with malignant tumours of the head and neck, following four weeks of radiotherapy at tygerberg hospital. The benefit of saliva substitutes to ameliorate the effects of …
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A cross-over randomised controlled trial of selective pressure impressions for lower complete dentures and laboratory investigations into impression pressure variation
… for complete dentures, especially in the form of randomised controlled trials (Jokstad et al 2002, Harwood 2008). The literature review from Part I suggested that selective pressure impressions for complete dentures required evidence on three levels; firstly, in-vitro evidence on the numerous …
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How much Detail is needed in Cost Estimation in an Economic Evaluation alongside a Clinical Trial to Optimise Evidence for Decisions?
… Collecting resource use data alongside a randomised controlled clinical trial is particularly so due to the multidimensional nature of costs: different costs are incurred by different agencies with varying methods and systems to account for these. Trialists are faced with decisions over …
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Effects of xanthine oxidase inhibitors in pulmonary hypertension associated with chronic lung disease
… chronic lung disease (PH-CLD).In a double-blind, randomised controlled clinical trial, 72 patients with PH-CLD (93% diagnosed with chronic obstructive pulmonary disease and 17% with interstitial lung disease) were randomised to receive either allopurinol 300 mg twice daily or placebo for twelve …
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Diabetes in children: impact of an innovative pharmaceutical care programme and links with concurrent illnesses
… mellitus.<br/><br/>The main body of work was a randomised controlled trial carried out at Hamad General Hospital (HGH), Qatar. This study included 212 children ≥ 18 years of age with T1DM (Chapter 2). Those randomised to a pharmacist-managed clinic received education from a pharmacist on their …
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Allopurinol as a possible oxygen sparing agent during exercise in peripheral arterial disease
… with PAD.<br/><br/>In a double-blind, randomised controlled clinical trial 50 participants with PAD were randomised to receive either allopurinol 300mg twice daily or placebo for six months. The primary outcome was change in exercise capacity on treadmill testing at six months. …
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The effect of vitamin K On vascular health and physical function in older people with vascular disease
… vascular disease.<br/><br/>In a double-blind randomised controlled clinical trial 80 participants aged ≥ 70years with established vascular disease were randomised to receive 100mcg vitamin K or placebo daily for 6 months. The primary outcome was a between group difference in endothelial …
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The effect of spironolactone on exercise capacity in functionally impaired older people without heart failure
… people without heart failure. In a double-blind, randomised controlled clinical trial 120 participants, aged >65 years with functional impairment were randomized to receive 25mg spironolactone or placebo for 20 weeks. The primary outcome was the change in six-minute walking distance over 20 weeks. …
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Developing evidence-based decision making for tooth replacement in partially dentate patients
… class="MsoNormal">A systematic review of randomised and non-randomised controlled trials was conducted to evaluate studies of the effectiveness of different tooth replacement strategies in adult patients with shortened dental arches. A protocol was registered with the International …
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Whānau Pakari: a multi-disciplinary intervention for children and adolescents with weight issues
… using a mixed methods approach, incorporating a randomised clinical trial. Whānau Pakari means “healthy, self-assured families that are fully active”. The programme specifically targeted those over-represented in obesity statistics, namely Māori and those from most deprived households in the …
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Left Ventricular Diastolic Function in Adolescents with Overweight and Obesity: The Moderating Influence of Physical Activity, Cardiorespiratory Fitness, and Metabolic Health
… of routine VPA that might be tested in a randomised, controlled clinical trial as a means to normalise LVDF.
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Different dietary approaches for the treatment of obesity and the phenotypic responses to these diets.
… and cardiovascular disease risk factors. A randomised controlled trial investigating dietary approaches for the treatment of obesity and its co morbidities was carried out. Variables including weight and body composition, cardiovascular risk factors, adipokines, liver and kidney function, …
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Improving outcomes for women with endometriosis
… age. It is defined by the presence of endometrial-like tissue (lesions) found outside the uterine cavity, usually within the pelvis. The most widely reported symptoms of endometriosis are chronic pelvic pain and infertility. Endometriosis-associated pain can have a significant and …