Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 308 for “"Randomised Controlled Trial"”.
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Novel methods within a randomised controlled trial in respiratory disease
Introduction:<br/>A well designed randomised controlled trial is the best-known process to assess if a healthcare intervention works. The number of clinical trials registered and open for recruitment is increasing every year, through the global cumulative effort of many researchers and the large …
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‘Forging a conviction’ – participants’ experiences of a western acupuncture randomised controlled trial
… a qualitative study, nested within a large randomised controlled trial of<br/>acupuncture specifically designed to investigate both specific and non-specific<br/>effects of western acupuncture for osteoarthritis pain. The aim was to explore the<br/>non specific effects of acupuncture in a …
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Evaluating breastfeeding support : a randomised controlled trial of support from breastfeeding counsellors
… the commonest reason for stopping. Study two, a randomised trial of support from breastfeeding counsellors, recruited 720 women. At four months, 46.1% (143/310) intervention and 42.3% (131/310) control women breastfed (Chi\(^2\)=0.942, P=0.33); 73.9% (229/310) vs 79.4% (246/310) gave bottle feeds …
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ASpirin as a treatment for ARDS (STAR): a phase 2 randomised controlled trial
… <br/><br/>Objectives: <br/>The aim of the STAR trial (aSpirin as a Treatment for ARDS) was to test the hypothesis that enteral aspirin 75mg was both safe and effective in improving important surrogate outcomes in adult patients with ARDS. <br/><br/>Methods:<br/>This randomised, double blind …
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Effect of atorvastatin on asthma control and airway inflammation: a randomised controlled trial
… asthma were recruited to a 22-week crossover randomised controlled trial comparing the effect on asthma control and airway inflammation of oral atorvastatin 40 mg daily with that of a matched placebo. Each treatment was administered for 8 weeks separated by a 6-week washout period. The primary …
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Extending the clinical and economic evaluations of a randomised controlled trial: The IONA Study
… a treatment is clinically effective a clinical trial is carried out and this is now usually accompanied by an economic evaluation, so that the cost effectiveness of the treatment can be assessed. When a clinical trial aimed at preventing clinical events is analysed, a time-to-first event …
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Evaluation of the Parent Centre's positive parenting skills training programme: a randomised controlled trial
… homework checklists for each session. A randomised controlled trial design was used to assess programme outcomes; pre and post-test interviews were conducted in people's homes which utilised a range of measures. The programme was found to be implemented with high levels of fidelity. …
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A randomised controlled trial of Absorbatox TM C35 in irritable bowel syndrome: a pilot study
… properties, in the treatment of IBS in a 6-week randomised , double-blind, placebo-controlled trial with parallel group assignment. Methods: Ethical approval for the study was received (Ethical approval number NWU-0001- 008-S5) and the necessary consent from trial candidates were received as per …
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Comparison of short-term outcomes between two sacrospinous suture capture devices : a randomised controlled trial
… dissection to perform this procedure. METHODS A randomised controlled trial was carried out comparing the Boston Scientific's Capio Slim® (control) and Bard's Fixt® (intervention) for bilateral sacrospinous fixation in women with mid-compartment prolapse requiring surgery and who met the study …
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An innovative resuscitation training strategy for primary care nurses: feasibility study for a randomised controlled trial
… post-doctoral, statistically-powered, full-scale randomised controlled trial to assess the effect of the new resuscitation training intervention will deliver maximum benefit. The development of a cost-effective, optimal model of resuscitation training should provide the best care for patients, …
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Anxiety and it's management during awake procedures in operating theatres. A survey and randomised controlled trial.
… anxiety. The second stage of the study was a randomised controlled trial of interventions for the effective management of intra-operative anxiety in patients (n=128) having undergone the same surgical procedures described in stage one. The interventions tested in stage two were handholding and …
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A randomised controlled trial to assess the pain associated with the debond of orthodontic fixed appliances
Objectives: To determine patients' experiences of pain during treatment with fixed appliances, expectations of pain during debond and whether biting on a soft acrylic wafer during debond decreases the pain experienced. Method: Ethical approval was gained. Subjects were randomly allocated to the …
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The Development and efficacy of cognitive behaviour therapy for multiple sclerosis fatigue: a randomised controlled trial
… treat MS fatigue. The purpose of the randomized controlled trial (RCT) was to investigate the efficacy of CBT compared to relaxation training (RT) to treat fatigue in MS. Methods Seventy-two patients with MS fatigue were randomly assigned to either eight sessions of CBT or eight sessions of RT, …
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Impact of long-acting contraceptives on female genital tract cytokine profiles in a randomised controlled trial
… Contraceptive Options and HIV Outcomes (ECHO) trial found no substantial difference in HIV acquisition risk between women randomised to injectable depot medroxyprogesterone acetate (DMPA-IM), copper intrauterine device (IUD) or the levonorgestrel (LNG) implant. However, it remains unknown …
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Improving cardiac rehabilitation session attendance using the Self-Regulatory Model and motivational interviewing: A randomised controlled trial
… perceptions, and to enhance motivation. Design: Randomised, controlled trial. Participants: Patients attending for their first Phase III CR class were recruited. Outcome Measures: The primary outcome measure was the number of rehabilitation exercise sessions attended, providing data on …
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Eccentric cycling rehabilitation after anterior cruciate ligament reconstruction: a randomised controlled trial of strength and biomechanical outcomes
… chronic, clinical changes in joint loading. A randomised controlled intervention trial evaluated progressive eccentric cycling for ACL-R males, compared to concentric controls. This is one of the first trials of eccentric vs. concentric training for ACL-R, matched by rating of perceived …
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A randomised controlled trial of N-acetylcysteine in the management of anti-tuberculosis drug-induced liver injury
… We conducted a randomized double-blind placebo-controlled trial of intravenous NAC in adult hospitalized participants with AT-DILI. Primary endpoint was time to ALT < 100 U/L; secondary endpoints included length of hospital stay and 8-week mortality. We described outcomes of ATT rechallenge …
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A randomised controlled trial of a diet and physical activity intervention in prostate cancer patients and related studies.
… is to present the rationale and methodology of a Randomised Controlled Trial (RCT) to test the efficacy of a 6 month combined dietary and walking intervention on alleviating the Health-Related QoL (HRQoL) issues associated with ADT treatment. Ninety-four men were recruited and randomised to the …
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A randomised controlled trial comparing two models of medication review in older patients in a community pharmacy setting
A randomised controlled trial design was chosen to compare a model of community pharmacy based clinical medication review (CMR) with no access to information from patients’ medical records (active) with a model which had access to information from patients’ medical records (control). Four hundred …
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