Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 92 for “"Randomisation"”.
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Development of the MAX randomisation technique
… be screened for desired or novel activities. Randomisation in this fashion has predominantly been achieved by the inclusion of the codons NNN or NNGCor T, in which N represents any of the four bases A,C,G, or T. The use of thesis codons however, necessities the cloning of redundant codons at …
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The Impact of Randomisation in Load Balancing and Random Walks
The real world is full of uncertainties. Classical analyses usually favour deterministic cases, which in practice can be too restricted. Hence it motivates us to add in randomness to make models similar to practical situations. In this thesis, we mainly study two network problems taken from the …
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Towards More Accurate Causal Inference with Instrumental Variables and Mendelian Randomisation Analyses
… in epidemiological studies is known as Mendelian Randomisation (MR). The conventional modelling assumption for using IVs is to assume a linear structural equation model between the exposure and the outcome. In recent years, there have been various developments in the literature that attempt to …
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Development of a Random Time-Frequency Access Protocol for M2M Communication
… collision problem in these systems.<br/><br/>The randomisation algorithm, used to access channels in the frequency domain, represents the key factor that affects data collisions. This thesis presents a new randomisation algorithm for the channel selection process for M2M technologies. The new …
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The role of subgroups and sub-populations in drug development and drug regulation
… environment.<br></br><br></br>In Chapter Two, randomisation is reviewed in relation to unbiased estimation of treatment differences and the impact of data exclusion to form subsets is described.<br></br><br></br>Simpson's paradox (SP) is considered in Chapter Three. Randomisation is shown to …
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Renal and Blood Pressure Effects of Xanthine Oxidase Inhibitors in the FAST trial
… to achieve EULAR recommended sUA levels prior to randomisation. The up-titration process involves increasing allopurinol dose by 100mg and re-checking sUA after 2 weeks. Dose increases of 100mg are repeated every fortnight until sUA is <357 µmol/L or the patient is taking their maximum tolerated …
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The feasibility and potential effectiveness of a conventional and exergame intervention to alter balance-related outcomes including fall risk: a mixed methods study
… employed feasibility RCT methodology. Cluster randomisation assigned interventions to sites. Single blinding was used. Both interventions were offered for six months. A variety of balance-related endpoints (e.g., Timed Up and Go, Dynamic Gait Index, Mini-BESTest) were used to find the most …
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Development and Validation of Experimental Protocol and Guidelines for Non-Invasive Superficial and Deep Muscle Electromyography in the Forearm
… investigated that varied the effects of timing, randomisation and movement anticipation on the ability of the sdEMG technique to detect and isolate the superficial muscles flexor digitorum superficialis (FDS) and extensor digitorum (ED), and the deep muscles extensor indicis (EI), extensor …
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End-to-end deep reinforcement learning in computer systems
… experiment protocol called progressive randomisation which helps practitioners to incrementally evaluate different dimensions of non-determinism. I demonstrate how Wield and progressive randomisation can be used to reproduce and assess prior work, and to guide implementation of novel RL …
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Phytosterol-enriched margarine substitution in the management of familial hypercholesterolaemia
… the collection of baseline data, visit 2 the randomisation to either of the regular of phytosterol margarine periods, visit 3 for the cross-ver to the alternative margarine form, visit 4 marked the onset of washout period and visit 5, was the last evaluation visit. Margarine use was in …
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Functional analysis and modelling of vegetation: plant functional types in a mesocosmos experiment and a mechanistic model
… types. New null models are developed for this randomisation method and their statistical properties are investigated. The mechanistical model LEGOMODEL is used to simulate the succession of plant functional types using the 'Leaf-Height-Seed Scheme'. This classification scheme uses only the …
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Clonal haematopoiesis of indeterminate potential and the role of inflammation in its association with atherosclerosis
… in combination with null results in Mendelian randomisation analysis suggests that reverse causation does not underly the relationship between CVD and CHIP. We also find that CHIP does not universally drive augmented atherogenesis in experimental models, uncovering gene-specific sexual …
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The impact of play-informed caregiver-implemented home-based intervention on the academic learning outcomes for HIV positive children (aged 5 years to 8 years) on Antiretroviral Therapy (ART) living in low income conditions: a randomized control trial
… leaving 26 dyads that went through the randomisation and allocation process into the two intervention groups. Randomisation was carried out by a central computer system, before the start of the intervention period. The final total sample (n=23) completed the intervention, a slight …
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Auswirkungen einer thorakalen Periduralanästhesie auf Perfusion und Oxygenierung der Leber : eine tierexperimentelle Studie
… Periduralkatheter auf Höhe von Th8 gelegt. Per Randomisation erfolgte die Zuteilung in drei Gruppen: PDA allein (n=8), PDA mit Volumengabe (n=9), Kontrollgruppe (n=3). Messungen erfolgten nach 60 und 120 Minuten. Ergebnisse: Weder die Periduralanäasthesie allein, noch in Kombination mit …
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Comparison of the effects of manual acupuncture, electroacupuncture and TENS on regional pressure pain thresholds : examination of the reliability of baseline alogmetry pressure pain threshold readings
… that used the same research paradigm including randomisation and dual blinding (subject and assessor) and involved healthy volunteers. PPT was measured before and after each intervention at ten PPT measurement sites (both acupoints and nonacupoints) across the body. In addition, subjects rated …
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Characterising disease-related and developmental changes in correlation-derived structural and functional brain networks
… Previous studies reported increased network randomisation in schizophrenia, but these results may have been driven by inclusion of a greater number of noisy edges in patients’ networks, based on retention of a fixed proportion of the strongest edges during network thresholding. Here, a novel …
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Do Marketing Strategies Impact Condom Sales in Uganda?
… study, we use the method of Wild Bootstrap-6 pt Randomisation Inference to discuss the statistical significance of our results.</p>
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Mutationen in DNAH5 verursachen Primäre Ziliäre Dyskinesie
… weist einen Situs inversus auf, der über eine Randomisation der Links-Rechts Körperasymmetrie resultiert (Kartagener Syndrom). Elektronenmikroskopisch lassen sich ultrastrukturelle Defekte in den Zilien der meisten Patienten entdecken. Darunter scheinen v.a. Defekte der Dyneinarme …
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Non-Metric Multi-Dimensional Scaling for Distance-Based Privacy-Preserving Data Mining
… method provides an adequate alternative to data randomisation approaches and other dimensionality reduction approaches. Testing is conducted on a wide range of benchmarked datasets and against some existing perturbation methods. The results confirm that our method has very good overall …
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A partially-automated approach to the assessment of mathematics in higher education
… over other approaches, for example question randomisation allows individualisation of assessment, but it is restricted in the range of what can be assessed due to the limitations of automated marking. A partially-automated approach is proposed in which e-assessment techniques are used to set …
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