Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Ran inhibition"”.
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The effect of RAN inhibition on human colorectal cancer cells (CRC)
… study aimed to assess the hypothesis that the Ran inhibitor mebendazole MBZ reduces cell invasion and metastasis of CRC. I have investigated MBZ effect on the CRC isogenic human cell lines with specific mutations (HCT-116 K-Ras, DLD-1 K-Ras and Pten deletion and wild type HCT-116 and DKO-3. I …
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The Effect of Mebendazole and RAN Mediated Pathways on Human Breast Cancer Cells
… lungs, and brain as the most frequent sites. Ran, a protein highly expressed in cancer cells, facilitates cell invasion, metastasis, and drug resistance. This study investigated the hypothesis that Mebendazole has anti-cancer activity via Ran and has antiangiogenic effects, which can be …