Global ETD Search
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Showing 1 to 6 of 6 for “"Ramachandran plot"”.
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Recombinant expression, purification and structural characterization of aspergillus niger ring finger domain using nuclear magnetic resonance spectroscopy
… predicted 3D model was validated by analyzing a Ramachandran Plot, which indicated 88.0 % of the residues are in the most favoured region. This is very close to the 90% widely accepted mark of 3D models indicative of excellent quality models. Added to this, eight B-cell epitopes were predicted …
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Investigation of Interaction between heat shock protein 70.14 (Hsp 70.14) and RBBP6 RING finger domain
… homology modelling and subsequent validation by Ramachandran plot revealed that modelled structures were of good quality. Molecular docking studies show a strong interaction between the two proteins with a high binding score (KD) of 16038. The recombinant proteins were successfully expressed in …
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Recombinant expression, purification and structural characterization of Saccharomyces cerevisiae RING finger domain using Nuclear Magnetic Resonance (NMR) spectroscopy
… extent. Validation of the predicted model by Ramachandran plot showed that 88% of the amino acids residues are in the favoured region meaning that the modelled structure is an acceptable representation of the S. cerevisiae RING finger protein.More so, interacting partners for S. cerevisiae …
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Structural Characterization of the Switch domain regions of Schistosoma mansoni druggable Adenylate cyclase-stimulating Gα-protein
… stereochemical parameters as evaluated by the Ramachandran plot analysis in RAMPAGE reveals that the modelled structure is stable and of good quality. Docking studies revealed the binding and interaction patterns of the switch domains protein with guanosine-5'-triphosphate, magnesium, calcium …
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Structural Determination of the novel Universal Stress Protein G4LZI3 from Shistosoma mansoni using X-ray Crystallography
… to the C-terminal of the protein. A generated Ramachandran plot showed that though there is still room for improvement, the solved structure is a relatively good model with 92% of the residues present in the favored and allowed regions. Inferred function points towards the protein binding ATP …
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A Computational Framework for Interacting with Physical Molecular Models of the Polypeptide Chain
Although nonflexible, scaled molecular models like Pauling-Corey's and its descendants have made significant contributions in structural biology research and pedagogy, recent technical advances in 3D printing and electronics make it possible to go one step further in designing physical models of …