Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 559 for “"Radiotherapy"”.
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Optimization of Gold Nanoparticles for Radiotherapy
Radiotherapy is currently used in around 50% of cancer treatments. Although highly effective it is also damaging to surrounding healthy tissues and needs to be improved by better targeting of cancer cells. Improved radiotherapy outcomes can be achieved by using nanoparticles, especially those with …
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Modelling geometric uncertainties in prostate radiotherapy
Image guided radiotherapy (IGRT) presents a range of techniques to enhance thegeometric accuracy of radiotherapy treatment. A full evaluation of such techniques,against increased cost, workload, or unnecessary radiation dose, would require theincorporation of geometric errors into existing methods …
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Multicriteria Optimization in Inverse Radiotherapy Planning
The development of intensity-modulated radiotherapy (IMRT) has greatly enhanced the possibilities of shaping the dose distribution. However, because of physical limitations, even with IMRT a certain dose to organs at risk is unavoidable, so in treatment planning often a compromise between different …
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Characterization of brain response following cranial radiotherapy
Cranial radiotherapy (CRT) is a vital component for the treatment of pediatric brain tumors, with combination therapy that includes CRT resulting in almost 90\% five-year survival. However, survivors treated with CRT exhibit alterations in brain development and long-term deficits in brain structure …
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Efficient and Intelligent Radiotherapy Planning and Adaptation
… tomography images--is the foundation of modern radiotherapy. Contouring planning structures and optimizing plan dose distributions are the two most important components of treatment planning. Treatment planning happens in two stages. The initial treatment plan is first designed before the …
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Treatment Planning Automation For Rectal Cancer Radiotherapy
… population of the world lack adequate access to radiotherapy treatments which is a part of the standard of care for rectal cancers. Safe radiotherapy treatments require specialized planning expertise and are time-consuming and labor-intensive to produce.</p> <h2>Purpose:</h2> <p>To alleviate the …
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Radiotherapy in Non-Small-Cell Lung Cancer
Contains fulltext : 30924_radiinnol.pdf (Publisher’s version ) (Open Access)
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Radiotherapy induced toxicity in lung cancer patients
Contains fulltext : 194287.pdf (Publisher’s version ) (Open Access)
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Intensity modulated radiotherapy for skull base meningioma
… is to optimise and preserve CNS function. Radiotherapy is an effective treatment for meningioma, with doses of 50-54Gy in conventional fractionation schedules resulting in long-term local control rates of 80-90%. However, local recurrence is unacceptably high in aggressive histological …
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Advancing Radiotherapy Treatment Through Artificial Intelligence-Driven Approaches
Radiotherapy is a critical treatment regimen for cancer patients. Modern radiotherapy aims to deliver precise radiation doses to specific tumor target volumes while minimizing exposure to surrounding healthy tissues and organs. To achieve precision and high treatment quality, accurate target …
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Automated to ols for Contour Review in Radiotherapy
<p>Peer review of organ-at-risk and target volume delineation is essential for patient safety and optimization of treatment outcomes. Peer review makes a substantial impact on patient outcomes, reporting notable rates of plan changes when reviewed and worse survival when patient cases are not …
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Thoracic Radiotherapy Treatment Planning With Cine Pet/Ct
… motion causes substantial uncertainty in radiotherapy treatment planning. Four-dimensional computed tomography (4D-CT) is a useful tool to image tumor motion during normal respiration. Treatment margins can be reduced by targeting the motion path of the tumor. The expense and complexity of …
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Proteomic identification of putative biomarkers of radiotherapy resistance
BackgroundCurrently, tumour response to radiotherapy cannot be predicted meaning that those patients with tumours resistant to the therapy endure the harmful side effects associated with ionising radiation in the absence of therapeutic gain. The aim of this project was to identify protein …
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Stromal-epithelial dynamics in response to fractionated radiotherapy
Radiotherapy is central to the management of a number of human cancers, either as an adjuvant or primary treatment modality. The principal objective in irradiating tumors is to permanently inhibit their proliferative ability. More than half of all malignancies are primarily treated with radiation, …
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Beyond The Dvh - Spatial And Biological Radiotherapy Treatment Planning
… SABER is able to distinguish features of radiotherapy treatment plans not discernible using commercial systems. Plans that have similar DVHs may have different spatial and biological characteristics, and the application of novel tools such as sDVH and DCF within SABER and the choice of …
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