Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Radiogenomics"”.
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Unravelling the Spatial and Temporal Heterogeneity of High-Grade Serous Ovarian Cancer Using Imaging-Based Biomarkers
… addresses technical barriers in integrating radiogenomics into HGSOC clinical settings, as well as leveraging radiomics for treatment response prediction. It includes four technical contributions, with a comprehensive background chapter introducing concepts and challenges in HGSOC, Computed …
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From genotype to phenotype: novel methodologies for the discovery of new pathological biomarkers in human
… Finally, Chapter 5 introduces the field of radiogenomics, a promising approach studying the relationship between the imaging and genome-related characteristics of a disease, and provides the preliminary results of a study on patients with dementia and Alzheimer's disease that underwent …
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Machine learning-driven integration of multimodal data for deciphering breast cancer heterogeneity
… genomics, multi-genomics, to proteomics and radiogenomics. We have four major objectives: 1)human epidermal growth factor receptor2 positive/estrogen receptor-positive (HER2+/ER+) BC stratification and prognostic gene signature identification using single genomic data; 2) BC subtyping using …
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Bayesian Kernel Models for Statistical Genetics and Cancer Genomics
… explore the potential of these approaches in radiogenomics, a brand new subfield of genetics and genomics that focuses on the study of correlations between imaging or network features and genetic variation.</p>
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Bayesian Integrative Analysis of Omics Data
… establishment in integrative analysis of radiogenomics and pathway driver detection applied in cancer applications. We initially present Radio-iBAG that utilizes Bayesian approaches in analyzing radiological imaging and multi-platform genomic data, which we establish a multi-scale Bayesian …
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Integration of multi-omic data and neuroimaging characteristics in studying brain related diseases
… production in the field of imaging genetics and radiogenomics. Studies in these fields have taken different designs and directions from genomewide associations to studying the complex interplay between genetics and structural connectivity of a wide range of brain-related diseases. Nevertheless, …
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Risk stratification in the management of localised prostate cancer treated with radical radiotherapy
… the more advanced of the two) and biology-based ‘radiogenomics’. The work reported here investigates both aspects of this topic in the context of localised prostate cancer, the management of which has changed greatly in recent years. Radical radiotherapy and radical prostatectomy remain the …
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Characterising Heterogeneity of Glioblastoma using Multi-parametric Magnetic Resonance Imaging
A better understanding of tumour heterogeneity is central for accurate diagnosis, targeted therapy and personalised treatment of glioblastoma patients. This thesis aims to investigate whether pre-operative multi-parametric magnetic resonance imaging (MRI) can provide a useful tool for evaluating …