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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Radiation biology"”.
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Investigation and use of dual (twin) low pressure proportional counters for active neutron-gamma mixed field dosimetry
… accurate neutron-gamma mixed field dosimetry in radiation protection and radiation biology. While passive dosimeters are suitable for measuring low radiation levels, active instruments are necessary in high radiation environments, such as found in nuclear power plants and particle accelerator …
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Characterizing in vitro propagation and radiation response of murine mammary stem cells
… be sensitive to known carcinogens (i.e. ionizing radiation), which impact their susceptibility to transformation. The involvement of mammary stem cells in tumorigenesis could explain the heterogeneity and molecular complexity of breast cancer. However, the involvement and the underlying mechanisms …
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Mechanisms Regulating Pulmonary Sensitivity to Radiation
… or treating pneumonitis/fibrosis following acute radiation exposure. Since it is neither ethical nor feasible to evaluate potential MCMs against radiation injury in the clinical setting, the FDA permits MCM licensure under an alternative drug development pathway ("Animal Efficacy Rule") that …
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Transkriptomweite Untersuchungen von Prostata-Krebszelllinien im Kontext medizinischer Strahlentherapie
Die Strahlentherapie ist neben der Chemotherapie und einer operativen Entfernung die stärkste Waffe für die Bekämpfung bösartiger Tumore in der Krebsmedizin. Nach Herz-Kreislauf-Erkrankungen ist Krebs die zweithäufigste Todesursache in der westlichen Welt, wobei Prostatakrebs heutzutage die …
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Examination of molecular genetic factors involved in sensitivity to breast cancer following radiation exposure
… repair is not only an important aspect of cell biology, but also has important implications for the field of carcinogenesis since cancer most likely occurs from genetic damage that occurs over one's lifetime. DNA repair needs to be accurate and efficient in order for a cell to maintain genomic …
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Facilitating the Clinical Translation of Flash Radiotherapy Through Dosimetry Development and Beam Parameter Optimization
<p>Advisory Professor: Emil Schüler, PhD</p> <p>Radiation therapy (RT) is a crucial component of curative cancer therapy, with a majority of cancer patients in the United States receiving RT as part of treatment. The goal of RT is to maximize the therapeutic index in curing disease while minimizing …
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The Importance of Dna Repair Capacity to (And A Model to Predict) Cell Radiosensitivity to Ions
<p>Radiation therapy with ions has a number of advantages over conventional radiation therapy with photons, including favorable depth-dose distributions, greater relative biological effectiveness (RBE) and a lesser dependence on a number of biological factors known to affect radiosensitivity to …
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Prophylactic Cranial Irradiation Reduces The Incidence of Brain Metastasis In A Mouse Model of Metastatic Breast Cancer
<p>Prophylactic cranial irradiation (PCI) is a preventative whole-brain irradiation technique used to reduce the incidence of brain metastasis and improve overall survival in select patients with small cell lung cancer and acute lymphoblastic leukemia. A population of breast cancer patients – stage …
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Modification of fecundity and fertility during oogenesis by gamma radiation and/or ozone with a cytological analysis in the ectoparasitic wasp, Habrobracon juglandis (Ashmead)
… to 0, 25, 35, 45, and 65 Gy of Co-60 gamma radiation. All treated wasps showed significant progressive decreases in fecundity and fertility with increases in radiation dose; females given 45 and 65 Gy experienced temporary infecundity and permanent sterility, respectively. The results …
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Bystander Effects Due To Neutrons, And Low-Dose Hyper-Radiosensitivity To Gamma Rays In Human Cells Using Cytogenetics
… such as nucleoplasmic bridges and nuclear buds. Radiation-induced clastogenic events were evaluated via the cytokinesis-block micronucleus assay in two normal human lymphoblastoid cell lines exposed to neutrons or gamma radiation. Micronuclei, nucleoplasmic bridges and nuclear buds were …