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Showing 1 to 2 of 2 for “"RacGAP"”.

  1. RacGap50C Is a Novel Negative Regulator of Wnt Signaling

    … epidermal patterning carry mutations in the RacGap50C gene. These mutations on their own cause cuticle pattern disruptions that include replacement of ventral denticles with naked cuticle, which indicate that the Wg pathway is ectopically activated in mutant embryos. In addition, RacGap50C …

    duke Repository record for RacGap50C Is a Novel Negative Regulator of Wnt Signaling (opens in a new tab)

  2. Actions of alpha-chimaerins in mechanisms relevant to dendritic spine formation and neurodegeneration

    Rho GTPases and their regulators such as guanosine exchange factors (GEFs) and GTPase activating proteins (GAPs) represent an important class of molecules controlling dendritic spine plasticity. Although they are typically described as cytoskeletal modulators, roles for the GTPases in endocytosis …

    cambridge Repository record for Actions of alpha-chimaerins in mechanisms relevant to dendritic spine formation and neurodegeneration (opens in a new tab)