Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Rac2"”.
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Study of the murine RAC2 promoter
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Hematopoietic-specific regulation of the human hex1/hex02 human rac2 genes
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Identification of a Minimal Cis-element and Cognate Trans-factors Required for the Regulation of Rac2 Gene Expression during K562 Cell Differentiation
… examines the molecular mechanisms regulating Rac2 gene expression during cell differentiation and identification of a minimal cis-element required for the induction of Rac2 gene expression during K562 cell differentiation. The Rho family GTPase Rac2 is expressed in hematopoietic cell lineages …
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Major Collateral Vessels Develop from Pre-existing Small Arteries through RAC2/NOX2 Independent Mechanisms
… between rodents and pigs. Chapter II utilized Rac2-/- and Nox2-/- mice to investigate the hypothesis that Nox2-NAD(P)H oxidase is required for major collateral growth subsequent to femoral arterial occlusion. Previous studies suggest bone marrow cell (BMC)-derived reactive oxygen species (ROS) …
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In vivo pool-based shRNA screens to identify modulators of disease progression in hematopoietic malignancies
… and suppression of these genes, which included Rac2, CrkL, and the poorly characterized actin monomer binding protein Twf, impaired lymphoma progression and tumor cell dissemination to sites of terminal metastatic disease. Additionally, suppression of Rac2 and Twf improved chemotherapeutic …
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Role of Rap and Rho GTPases in T-acute lymphoblastic leukaemia cell adhesion and migration
… depletion of Raplb but not Rap la, RhoA, Racl, Rac2 and Cdc42. These results suggest that statins and Raplb depletion could be used to reduce tissue invasion in T-ALL. In contrast to other Rho family proteins, the atypical Rho GTPases RhoU and RhoV are not prenylated but undergo palmitoylation …
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Transcriptome profiling of infected chickens with newly emerged genotype VI I Newcastle disease virus strains
… identified novel genes EGF, LPAR5, AGT, AGTR1, RAC2, CD4, CD3D, IL7R, NPY, GRM3, and GRAP2 as potential biomarkers. This study provides valuable information to help understand novel immune evading mechanisms of highly pathogenic NDV-GVII from a host-pathogen interaction point of view. …
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The genetics of anthracycline-induced cardiotoxicity in cancer patients
… rs8187710); HNMT (rs17583889); NCF4 (rs1883112): RAC2 (rs13058338) and RARG (rs2229774), and tested for correlation with clinical status and cardiac injury. Finally, a corollary study was conducted on a subset of patients in an attempt to determine whether cardiac biomarkers may be more sensitive …