Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Rab2"”.
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Cell Biology of the ICA69 protein family in Neurosecretory cells
… to investigate the interaction between ICA69 and Rab2, a small GTPase associated with the intermediate compartment and involved in the trafficking between the ER and the Golgi complex. ICA69 was shown to co-immunoprecipitate with Rab2 from INS-1 cells extracts. GST-pull down assays demonstrated …
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Investigating the trafficking of Golgi-resident glycosylation enzymes
… factors. The screen identified the Rab2 effector of unknown function FAM114A2. FAM114A2 and paralogous protein FAM114A1 were shown to specifically associate with early-Golgi membranes. A predicted ALPS motif was necessary for membrane association, presumably through non-specifically …
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Characterising the factors involved in ER-to-Golgi anterograde trafficking
… site localisation. I have discovered a novel Rab2 binding site at the C terminus of GM130, that can direct GM130 to the Golgi apparatus in addition to its canonical GRASP65-mediated localisation mechanism. I have also identified the 154-447 region of GM130 as contributing to ER exit site …