Global ETD Search
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Showing 1 to 20 of 51 for “"RTT"”.
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Analysis of the Position-Dependent Error in FTM RTT Indoor Navigation
… time measurement (FTM) of the round-trip time (RTT) of a signal between an initiator (smartphone) and a responder (Wi-Fi access point) provides a promising method for indoor positioning. Accurate indoor positioning is a requirement for a wide range of applications, such as asset tracking, indoor …
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Simultaneous Localization and Calibration in a Wireless Network of Uncooperative Nodes
… measure their signal round-trip-time (RTT). But as of 2023, few commercially-deployed Wi-Fi access points (APs) actually support the protocol. Using a one-sided RTT measurement technique that does not require cooperation from the AP, a mobile device can obtain distance measurements with …
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Contextual Insights into the Rett Syndrome Transcriptome
… in MECP2 are responsible for Rett syndrome (RTT), a severe X-linked neurological disorder characterized by loss of developmental milestones, intellectual disability and motor impairments. However, molecular insight into how these mutations affect the neuronal transcriptiome, disrupt neuronal …
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Evidence-Based Instructional Practices for Teachers of Children With Rett Syndrome – A Case Study
… (EBP) utilized for children with Rett syndrome (RTT) by a team of special educators in a rural elementary school was examined. Using a case study approach, three teachers in a severe classroom setting who teach a student with RTT were observed and interviewed. The researcher addressed the …
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Human induced pluripotent stem cell models of Rett Syndrome reveal deficits in early cortical development
Rett Syndrome (RTT) is a pervasive, X-linked neurodevelopmental disorder that predominantly affects girls. The clinical patient features of RTT are most commonly reported to emerge between the ages of 6-18 months and as such, RTT has largely been considered to be a postnatal disorder. The vast …
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THE INTERPLAY BETWEEN HPCAL4 AND MECP2: IDENTIFICATION AND CHARACTERIZATION OF A NOVEL PUTATIVE TARGET FOR RETT SYNDROME THERAPY
Rett Syndrome (RTT) is a severe neurodevelopmental disorder and the leading cause of intellectual disability in females with 1 in 10,000 births being affected. The symptoms start to manifest in between 6 and 18 months of age and these include intellectual disability, epilepsy and impairments of …
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Vitamin D Modulates Rett Syndrome Phenotypes and Underlying Cellular Pathways in an Mecp2-mutant Mouse Model
<p>Rett syndrome (RTT) is a progressive and severe X-linked neurodevelopmental disorder caused by mutations in the transcriptional regulator MECP2. There is currently no effective treatment for RTT. Female RTT patients develop relatively normally during the first 6-18 months of life, after which …
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Developmental trajectory of functional neocortical networks in an in vitro mouse model of Rett syndrome
Rett syndrome (RTT) is a neurodevelopmental disorder caused by loss-of-function MECP2 mutations, affecting ~1 in 10,000 female births. RTT causes progressive impairments in early life and has no cure. Despite known genetic origin in RTT, the mechanisms by which MECP2 mutations disrupt brain …
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Lung Defects Contribute to Respiratory Symptoms in a Mecp2-mutant Mouse Model of Rett Syndrome
Rett syndrome (RTT) is a progressive neuro-metabolic disorder caused by mutations in the X-linked gene, methyl-CpG-binding protein 2 (MECP2). After a period of seemingly normal post-natal development, RTT patients experience a developmental regression, consisting of loss of acquired verbal and …
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The Effect of Punishment Threat on Children's Ability to Resist Temptation to Transgress and Lie
… response to a resistance-to-temptation (RTT) task was investigated under three punishment threat conditions: negative consequence, removing an anticipated reward, and no explicit punishment. Ninety first and second graders participated in the RTT task and seventy-three parents completed …
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Cell-type specific contributions to Rett Syndrome : neuronal and astrocytic signaling and sensory processing
… the underlying genetic cause for Rett Syndrome (RTT), a devastating neurodevelopmental disorder that primarily affects girls. While the function of this transcriptional regulator remains elusive and complex, recent focus has turned to downstream signaling pathways as putative targets for novel …
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A brain-derived MeCP2 complex supports a role for MeCP2 in RNA processing
… neurodevelopmental disorder Rett Syndrome (RTT). To further understand MeCP2 and potential roles in RTT pathogenesis, we have employed a biochemical approach to identify the MeCP2 protein complexes present in the mammalian brain. Here we show that MeCP2 exists in at least four biochemically …
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NEURAL PRECURSOR/STEM CELL-BASED THERAPY: A NOVEL THERAPEUTIC APPROACH FOR THE TREATMENT OF RETT SYNDROME
Rett syndrome (RTT) is a postnatal progressive neurodevelopmental disorder with an incidence of 1:10,000 females born alive. It represents the most common genetic cause of severe intellectual disability in girls worldwide and it is caused by severe loss of function mutations in the MECP2 gene …
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MOLECULAR STUDY OF CHROMATINOPATHIES: THE CASE OF RUBINSTEIN-TAYBI AND RETT SYNDROMES
… deficit, while classic form of Rett syndrome (RTT) is caused by mutations in the reader MECP2. Both disorders show neurodevelopmental defects and 10 to 30% of patients remains without a molecular diagnosis. Methods: In this work, we aim at deepening molecular aspects involving RSTS and RTT …
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Reducing short flows' latency in the internet
… delay, like one or two round trip times (RTTs), may easily cause user frustration and lose usability of services. In the most desirable scenario, we want to finish these kinds of flows in one network RTT. Furthermore, we would like the network's RTT to be as close as possible to the speed …
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Studies on X chromosome inactivation and the X-linked disease Rett syndrome
(cont.) the RTT phenotype.
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INVESTIGATING THE ROLE OF DEFECTIVE CELL TO CELL COMMUNICATION MECHANISMS IN RETT SYNDROME PATHOGENESIS
Rett syndrome (RTT) is a devastating neurodevelopmental disorder representing the main cause of severe intellectual disability in girls worldwide. Over 95% of individuals suffering from a classic form of RTT carry sporadic mutations in the X-linked MECP2 gene, encoding for the methyl-GpC-binding …
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Dilute Nitride Quantum Engineered Solar Cells: For Next Generation of Multispectral Ultra-High Efficiency Si and III-V Photovoltaics
… efficiency of the purposed p-i-n GaAsPN/GaP RTT MQWs solar cell in conjunction with an existing 25.6% HIT silicon device has been simulated under 1 sun and AM 1.5 G spectrum and the results show the possibility of achieving an efficiency of above 33% with this type of device. To gain a better …
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Use case-based evaluation of software defined networking controllers
… an improvement of 13%). The studied metrics on RTT and throughput showed improvement in the reliability test equal to averages of 1.182 and 2.166 ms with two and three-controller deployment respectively and a throughput average of 20 GB/s. The results have displayed a positive impact in terms of …
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Architecture design and performance analysis of practical buffered-crossbar packet switches
… crosspoint buffer size and needs to be of size RTT in cells, L is the packet size. RTT is the round-trip time which is defined by the distance between line cards and switch fabric. When the switch size is large or RTT is not negligible, the memory amount required makes the implementation costly …
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