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Showing 1 to 1 of 1 for “"RSS Accessibility"”.
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The Role of Epigenetics in Regulating V(D)J Recombination and Allelic Exclusion
… rearrangement (recombination signal sequences, RSSs) must be made accessible to the recombination machinery. Moreover, once an antigen receptor locus has rearranged and produced a successful in-frame protein, a mechanism known as allelic exclusion prevents further recombination.</p><p>The …