Global ETD Search
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Showing 1 to 3 of 3 for “"RP105"”.
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CD180/RP105 Toll-like Receptor (TLR) mediated signalling in Chronic Lymphocytic Leukaemia
… including Toll-like receptors (TLR). CD180/RP105 is a membrane-associated orphan receptor that belongs to the TLR family, is expressed by professional antigen-presenting cells, and drives normal B-cell activation and proliferation. We have previously shown that approximately 60% of CLL …
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Modulation of Obesity and its Sequelae by Microbiome/Immune System Interactions
… context. Data presented here indicate that RP105, an endogenous negative regulator of TLR signaling, also regulated the development of diet-induced obesity (DIO) and its sequelae. When subjected to high fat diet (HFD) stress, RP105-/- mice gained significantly less weight and were thereby …
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Functional interaction between CD180 Toll-like receptor (TLR) and B cell receptor (BCR) in the biology of Chronic Lymphocytic Leukaemia (CLL)
… via a range of receptors, including TLR. CD180/RP105 is a membrane-associated orphan receptor of the TLR family which is expressed on various cells of the immune system including macrophages, peripheral blood monocytes, dendritic cells, naive and mature B cells and marginal zone/mantle zone B …