Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"ROS homeostasis"”.
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Mitophagy-Mediated Regulation of ROS Homeostasis During HSC Activation Contributes to Cell Fate
… show high levels of reactive oxygen species (ROS) and a higher proportion of cycling cells at steady state. Mitophagy-defective HSCs aberrantly accrued ROS only upon HSC activation, sensitizing them to apoptosis, cell cycle delay, and/or differentiation, ultimately resulting in failure of the …
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REEP5-MFN1/2 tethering in ER-mitochondria crosstalk
… to their essential roles in maintaining cellular homeostasis. MERCs facilitate critical processes, including lipid biosynthesis, calcium transfer, and mitochondrial dynamics, via specific protein complexes. Dysregulation of MERCs has been implicated in the pathogenesis of several neurodegenerative …
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Transcriptional regulators in stem cell biology
… suggesting that reactive oxygen species (ROS) may accumulate in melanocyte lineage cells in the absence of BMI1. Antioxidant treatment in mice partially rescued melanocytes, indicating that BMI1-dependent ROS homeostasis may support melanocyte expansion. These data demonstrate that BMI1 …
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DELETION OF THE Foxo1 GENE IN MOUSE PITUITARY GLAND AND THE EFFECTS ON SOMATOTROPE DIFFERENTIATION AND FUNCTION
… with transport of pyrimidine nucleotides across mitochondrial membrane and such transport is essential for mitochondrial DNA and RNA metabolism. Studies involving overexpression of Slc25a33 in human cells have shown it enhances cell size and mitochondrial thymidine triphosphate level but …